我国流行性乙型脑炎流行特征及其病毒基因型研究进展

doi:10.11853/j.issn.1003.8280.2024.06.022

中国媒介生物学及控制杂志 ›› 2024, Vol. 35 ›› Issue (6): 744-752.DOI: 10.11853/j.issn.1003.8280.2024.06.022

• 综述 • 上一篇

我国流行性乙型脑炎流行特征及其病毒基因型研究进展

闫文喆^1,2, 李晋宇^1,2, 郭玉红², 岳玉娟², 刘小波², 宋秀平², 鲁亮², 赵宁²

1. 山东大学齐鲁医学院公共卫生学院媒介生物控制学系, 山东济南 250012;
2. 传染病溯源预警与智能决策全国重点实验室, 中国疾病预防控制中心传染病预防控制所, 北京 102206

收稿日期:2024-01-05 出版日期:2024-12-20 发布日期:2024-12-20
通讯作者: 赵宁,E-mail:zhaoning@icdc.cn
作者简介:闫文喆,女,在读硕士,从事媒介生物传染病研究工作,E-mail:wzyan0808@163.com
基金资助:
广东省重点领域研发计划（2022B1111030002）；蚊媒病毒7种病原体多重核酸检测试剂盒（荧光PCR法）的研发与应用（2023-00627）；国家科技重大专项（2017ZX10303404006）

Research progress on the epidemic characteristics and virus genotypes of Japanese encephalitis in China

YAN Wen-zhe^1,2, LI Jin-yu^1,2, GUO Yu-hong², YUE Yu-juan², LIU Xiao-bo², SONG Xiu-ping², LU Liang², ZHAO Ning²

1. Department of Vector Biology and Control, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China;
2. National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China

Received:2024-01-05 Online:2024-12-20 Published:2024-12-20
Supported by:
Key-Area Research and Development Program of Guangdong Province (No. 2022B1111030002);Development and Application of Seven Types of Mosquito-borne Virus Detection Kit (Real-Time PCR Method) (No. 2023-00627);National Science and Technology Major Project of China (No. 2017ZX10303404006)

摘要/Abstract

摘要： 流行性乙型脑炎病毒（乙脑病毒）是在我国持续传播的重要虫媒病毒,其引起的流行性乙型脑炎（乙脑）是我国重要的公共卫生问题。多年来,虽然乙脑在我国已得到显著控制,但生态变化和疫苗接种等因素作用,使我国乙脑病例的地理分布、发病人群年龄结构等流行病学特征发生改变。乙脑病毒进化迅速,优势基因型从GⅢ 转变为GⅠ,给乙脑的防控工作带来挑战。该文对我国乙脑的流行特征及乙脑病毒的基因型研究进行综述,为乙脑防控提供参考。

关键词: 流行性乙型脑炎, 乙脑病毒, 流行, 基因型, 进化

Abstract: Japanese encephalitis virus (JEV) is an important arbovirus that continues to spread in China. Japanese encephalitis (JE) caused by JEV is one of the important public health problems in China. Over the years, despite significant control of JE in China, the geographical distribution of JE cases and the age structure of the affected population have changed due to ecological changes and vaccination. Moreover, JEV has evolved rapidly, and the dominant genotype has changed from GⅢ to GⅠ,which brings challenges to the prevention and control of JE. This paper reviewed the epidemic characteristics of JE and the genotypes of JEV in China, providing reference for the prevention and control of JE.

Key words: Japanese encephalitis, Japanese encephalitis virus, Epidemic, Genotype, Evolution

中图分类号:

闫文喆, 李晋宇, 郭玉红, 岳玉娟, 刘小波, 宋秀平, 鲁亮, 赵宁. 我国流行性乙型脑炎流行特征及其病毒基因型研究进展[J]. 中国媒介生物学及控制杂志, 2024, 35(6): 744-752.

YAN Wen-zhe, LI Jin-yu, GUO Yu-hong, YUE Yu-juan, LIU Xiao-bo, SONG Xiu-ping, LU Liang, ZHAO Ning. Research progress on the epidemic characteristics and virus genotypes of Japanese encephalitis in China[J]. Chinese Journal of Vector Biology and Control, 2024, 35(6): 744-752.

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我国流行性乙型脑炎流行特征及其病毒基因型研究进展

Research progress on the epidemic characteristics and virus genotypes of Japanese encephalitis in China

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