湖南省永兴县人体重点肠道蠕虫感染监测分析

doi:10.11853/j.issn.1003.8280.2024.01.015

摘要/Abstract

摘要： 目的分析湖南省永兴县人体重点肠道蠕虫感染情况，为寄生虫病防控提供科学依据。方法 2016－2020年在湖南省永兴县按东、西、南、北、中5个方位分别随机抽取1个乡镇的1个行政村，连续5年开展监测，每个监测点每年调查3周岁及以上常住居民至少200人；采用改良加藤厚涂片法检测肠道蠕虫虫卵，试管滤纸培养法鉴定钩虫虫种，透明胶纸肛拭法检测3～9岁儿童蛲虫卵。采用WPS Excel 2021软件建立数据库，SPSS 20.0软件进行统计学分析，感染率的差异比较采用χ²检验。结果粪检5 066人，检出人体重点肠道蠕虫感染136人，感染率为2.68%，其中蛔虫感染率为1.99%、钩虫0.24%、蛲虫0.20%、鞭虫0.18%和肝吸虫0.08%，未检出混合感染。钩蚴培养12份，结果均为美洲钩虫。透明胶纸肛拭法检查3～9岁儿童1 500人，蛲虫感染率为0.33%。2016－2020年永兴县人体重点肠道蠕虫总感染率分别为4.08%、1.97%、3.24%、1.10%和3.00%。结论湖南省永兴县人体重点肠道蠕虫感染处于低流行水平，但感染因素依然存在，仍需加强分类监测和寄生虫病防治知识宣传教育。

关键词: 人体肠道蠕虫, 感染, 监测分析, 永兴县

Abstract: Objective To investigate the prevalence of key human intestinal helminth infections in Yongxing County, Hunan Province, China, so as to provide a scientific basis for parasitic disease prevention and control. Methods An administrative village each from five townships (located in the eastern, western, southern, northern, and central regions, respectively) was randomly selected in Yongxing County, Hunan Province from 2016 to 2020. At least 200 permanent residents ≥3 years old were surveyed at each surveillance point every year. The intestinal worm eggs were examined by using the Kato-Katz technique. The hookworm species was identified by using filter paper culture. The pinworm eggs were examined by using the anal swab method with a transparent tape for children aged 3 to 9 years. WPS Excel 2021 software was used to establish the database, and SPSS 20.0 software was used to conduct statistical analysis. The infection rate was compared using the Chi-squared test. Results A total of 5 066 persons were examined for worms in feces, with a rate of key intestinal worm infections of 2.68% (136 cases). The infection rates for roundworms, hookworms, pinworms, whipworms, and liver flukes were 1.99%, 0.24%, 0.20%, 0.18%, and 0.08%, respectively. No co-infection was detected. The results of 12 hookworm larvae culture samples were all Necator americanus. The anal swab test detected a pinworm infection rate of 0.33% among a total of 1 500 children aged 3 to 9 years. The overall key intestinal worm infection rates from 2016 to 2020 were 4.08%, 1.97%, 3.24%, 1.10%, and 3.00%, respectively. Conclusion The key human intestinal worm infection rate is at a low epidemic level in Yongxing County, Hunan Province, but the infection factors still exist. It is necessary to strengthen categorical surveillance and promotion and education of parasitic disease prevention and control knowledge.

Key words: Human intestinal worm, Infection, Surveillance and analysis, Yongxing County

中图分类号:

朱韩武, 阳慧, 何德彪, 黄军校. 湖南省永兴县人体重点肠道蠕虫感染监测分析[J]. 中国媒介生物学及控制杂志, 2024, 35(1): 85-88.

ZHU Han-wu, YANG Hui, HE De-biao, HUANG Jun-xiao. Surveillance and analysis of key human intestinal helminth infections in Yongxing County， Hunan Province， China[J]. Chinese Journal of Vector Biology and Control, 2024, 35(1): 85-88.

参考文献

[1] 曾婷,吕山,田利光,等. 1990-2019年我国主要人体寄生虫病疾病负担变化趋势研究[J]. 中国血吸虫病防治杂志,2023,35(1):7-14,37. DOI:10.16250/j.32.1374.2023001.Zeng T,Lyu S,Tian LG,et al. Temporal trends in disease burden of major human parasitic diseases in China from 1990 to 2019[J]. Chin J Schisto Control,2023,35(1):7-14,37. DOI:10.16250/j.32.1374.2023001.(in Chinese)
[2] 何孝勤, 周一平, 段绩辉, 等. 永兴县农村居民肠道寄生虫感染现况调查[J]. 实用预防医学, 2006, 13(3):670-671. He XQ, Zhou YP, Duan JH, et al. Investigation on the current situation of intestinal parasitic infections among rural residents in Yongxing county[J]. Pract Prev Med, 2006, 13(3):670-671.(in Chinese)
[3] 陈颖丹,黄继磊,朱慧慧,等. 我国土源性线虫从高感染到低感染水平的防治历程[J]. 中国寄生虫学与寄生虫病杂志,2019,37(4):395-398. DOI:10.12140/j.issn.1000-7423.2019. 04.004.Chen YD,Huang JL,Zhu HH,et al. China's control process of soil-transmitted helminth infections from pandemic to low-endemic levels[J]. Chin J Parasitol Parasit Dis,2019,37(4):395-398. DOI:10.12140/j.issn.1000-7423.2019.04.004.(in Chinese)
[4] 朱韩武,周虹,谭徽. 2019年湖南省郴州市人群土源性线虫感染分析[J]. 疾病预防控制通报,2020,35(6):20-22,45. DOI:10.13215/j.cnki.jbyfkztb.2008012.Zhu HW,Zhou H,Tan H. Survey of infection with soil-transmitted nematode in Chenzhou city of Hunan province,2019[J]. Bull Dis Control Prev,2020,35(6):20-22,45. DOI:10.13215/j.cnki.jbyfkztb.2008012.(in Chinese)
[5] 国家卫生健康委员会. WS/T 791-2021钩虫检测及虫种鉴定标准钩蚴培养法[S]. 北京:中国标准出版社,2021.National Health Commission. WS/T 791-2021 Detection and identification standard of hookworm-Hookworm larvae coproculture techniques[S]. Beijing:Standards Press of China,2021.(in Chinese)
[6] 朱韩武,李成华,段良松. 湖南省郴州市人体重点寄生虫病原谱及感染现状调查[J]. 中国血吸虫病防治杂志,2017,29(1):80-82. DOI:10.16250/j.32.1374.2016075.Zhu HW,Li CH,Duan LS. Pathogen spectrum and epidemic status of major human parasites in Chenzhou city,Hunan province[J]. Chin J Schisto Control,2017,29(1):80-82. DOI:10.16250/j.32.1374.2016075.(in Chinese)
[7] 朱慧慧,黄继磊,陈颖丹,等. 2019年全国土源性线虫感染状况分析[J]. 中国寄生虫学与寄生虫病杂志,2021,39(5):666-673. DOI:10.12140/j.issn.1000-7423.2021.05.015.Zhu HH,Huang JL,Chen YD,et al. Analysis on endemic status of soil-transmitted nematode infection in China in 2019[J]. Chin J Parasitol Parasit Dis,2021,39(5):666-673. DOI:10.12140/j.issn.1000-7423.2021.05.015(in Chinese)
[8] 丁昕,金小林,茅范贞,等. 2016-2020年江苏省农村地区无害化卫生户厕改造效果评估[J]. 中国寄生虫学与寄生虫病杂志,2021,39(6):794-798. DOI:10.12140/j.issn.1000-7423. 2021.06.010.Ding X,Jin XL,Mao FZ,et al. Effect evaluation of innocent sanitary toilets improvement in rural areas of Jiangsu province during 2016-2020[J]. Chin J Parasitol Parasit Dis,2021,39(6):794-798. DOI:10.12140/j.issn.1000-7423.2021.06.010.(in Chinese)
[9] 黄继磊,张米禛,朱慧慧,等. 2016-2018年全国3~9岁儿童蛲虫感染监测[J]. 中国血吸虫病防治杂志,2020,32(1):54-59. DOI:10.16250/j.32.1374.2019239.Huang JL,Zhang MZ,Zhu HH,et al. National surveillance on Enterobius vermicularis infections among children at ages of 3 to 9 years in China from 2016 to 2018[J]. Chin J Schisto Control,2020,32(1):54-59. DOI:10.16250/j.32.1374.2019239.(in Chinese)
[10] 朱慧慧,诸廷俊,陈颖丹,等. 新型冠状病毒肺炎疫情对重点寄生虫病防控工作的影响[J]. 中国寄生虫学与寄生虫病杂志,2021,39(3):365-369. DOI:10.12140/j.issn.1000-7423.2021.03.011.Zhu HH,Zhu TJ,Chen YD,et al. The impact of COVID-19 epidemic on the control of important parasitic diseases[J]. Chin J Parasitol Parasit Dis,2021,39(3):365-369. DOI:10.12140/j.issn.1000-7423.2021.03.011.(in Chinese)
[11] 吴小红,田洪春,罗静雯,等. 2016-2021年四川省土源性线虫病时空分布特征[J]. 中国血吸虫病防治杂志,2022,34(5):484-492. DOI:10.16250/j.32.1374.2022141.Wu XH,Tian HC,Luo JW,et al. Spatio-temporal distribution characteristics of soil-transmitted nematodiasis in Sichuan province from 2016 to 2021[J]. Chin J Schisto Control,2022,34(5):484-492. DOI:10.16250/j.32.1374.2022141.(in Chinese)
[12] 何战英,王小梅,吴文婷,等. 2016-2020年北京市人体重点寄生虫感染监测分析[J]. 中国寄生虫学与寄生虫病杂志,2021,39(4):557-560,563. DOI:10.12140/j.issn.1000-7423. 2021.04.023.He ZY,Wang XM,Wu WT,et al. Surveillance and analysis of important human parasitic infections in Beijing during 2016-2020[J]. Chin J Parasitol Parasit Dis,2021,39(4):557-560,563. DOI:10.12140/j.issn.1000-7423.2021.04.023.(in Chinese)
[13] 邓积广,余水兰,农智,等. 2016-2019年广西百色市人体重点寄生虫病监测结果分析[J]. 中国寄生虫学与寄生虫病杂志,2021,39(3):342-346. DOI:10.12140/j.issn.1000-7423.2021.03.019.Deng JG,Yu SL,Nong Z,et al. Surveillance of key parasitic diseases in populations of Baise city in Guangxi from 2016 to 2019[J]. Chin J Parasitol Parasit Dis,2021,39(3):342-346. DOI:10.12140/j.issn.1000-7423.2021.03.019.(in Chinese)
[14] 朱慧慧,周长海,诸廷俊,等. 2015年我国城镇居民土源性线虫感染调查[J]. 中国血吸虫病防治杂志,2020,32(5):476-482. DOI:10.16250/j.32.1374.2020202.Zhu HH,Zhou CH,Zhu TJ,et al. Prevalence of soil-borne nematode infections among residents living in urban/town areas of China in 2015[J]. Chin J Schisto Control,2020,32(5):476-482. DOI:10.16250/j.32.1374.2020202.(in Chinese)
[15] 陈颖丹,朱慧慧,黄继磊,等. 我国土源性线虫病流行现状及新时期防控原则[J]. 中国血吸虫病防治杂志,2019,31(1):23-25. DOI:10.16250/j.32.1374.2018309.Chen YD,Zhu HH,Huang JL,et al. Status and working principals of soil-transmitted nematodiasis during new period in China[J]. Chin J Schisto Control,2019,31(1):23-25. DOI:10.16250/j.32.1374.2018309.(in Chinese)
[16] 余晴,潘浩,江莉,等. 上海市生态城市建设中重点寄生虫病潜在传播风险及应对[J]. 中国血吸虫病防治杂志,2022,34(5):531-536. DOI:10.16250/j.32.1374.2021217.Yu Q,Pan H,Jiang L,et al. Potential transmission risk of key parasitic diseases and responses to the risk during the construction of an ecological city in Shanghai municipality[J]. Chin J Schisto Control,2022,34(5):531-536. DOI:10.16250/j.32.1374.2021217.(in Chinese)
[17] 徐蔚莹,黄艳. 健康教育在华支睾吸虫病防治中的作用及前景[J]. 热带医学杂志,2022,22(1):141-144. DOI:10.3969/j.issn.1672-3619.2022.01.032.Xu WY,Huang Y. Role and prospect of health education in control and prevention of clonorchiasis[J]. J Trop Med,2022,22(1):141-144. DOI:10.3969/j.issn.1672-3619.2022.01.032.(in Chinese)
[18] 周瑞红,周杰,魏兰军,等. 岳阳市城区小学生血吸虫病防治健康教育现状调查[J]. 热带病与寄生虫学,2022,20(4):221-224. DOI:10.3969/j.issn.1672-2302.2022.04.009.Zhou RH,Zhou J,Wei LJ,et al. Investigation on the current situation of schistosomiasis health education in primary students in urban area of Yueyang city[J]. J Trop Dis Parasitol,2022,20(4):221-224. DOI:10.3969/j.issn.1672-2302.2022.04.009.(in Chinese)