蚊虫肠道微生物在辐照不育技术中的应用前景

doi:10.11853/j.issn.1003.8280.2023.04.025

中国媒介生物学及控制杂志 ›› 2023, Vol. 34 ›› Issue (4): 579-584.DOI: 10.11853/j.issn.1003.8280.2023.04.025

蚊虫肠道微生物在辐照不育技术中的应用前景

地里努尔·帕尔汗德¹^,²^,³(), 郑小英¹^,²^,³, 吴忠道¹^,²^,³, 潘文杰⁴, 张东京¹^,²^,³^,*()

1. 中山大学中山医学院寄生虫学教研室, 广东广州 510080
2. 中山大学热带病防治研究教育部重点实验室, 广东广州 510080
3. 国家原子能机构核技术(昆虫不育)研发中心, 广东广州 510080
4. 中大核昆生物技术(东莞)有限公司, 广东广州 510080

收稿日期:2022-12-12 出版日期:2023-08-20 发布日期:2023-08-17
通讯作者: 张东京
作者简介:地里努尔·帕尔汗德，女，维吾尔族，在读硕士，主要从事媒介蚊虫防制研究，E-mail：paerhand@mail2.sysu.edu.cn
基金资助:
国家自然科学基金(82002168);国家自然科学基金(82072308);第六批次核能开发利用项目(20201192)

Application prospect of mosquito gut microbiotas in the irradiation-based sterile insect technique

Dilinuer PAERHANDE¹^,²^,³(), Xiao-ying ZHENG¹^,²^,³, Zhong-dao WU¹^,²^,³, Wen-jie PAN⁴, Dong-jing ZHANG¹^,²^,³^,*()

1. Department of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong 510080, China
2. Key Laboratory of Tropical Disease Control of Ministry of Education, Sun Yat-sen University, Guangzhou, Guangdong 510080, China
3. Chinese Atomic Energy Agency Center of Excellence on Nuclear Technology Applications for Insect Control, Guangzhou, Guangdong 510080, China
4. Guangzhou SYSU Nuclear and Insect Biotechnology Co., Ltd., Guangzhou, Guangdong 510080, China

Received:2022-12-12 Online:2023-08-20 Published:2023-08-17
Contact: Dong-jing ZHANG
Supported by:
National Natural Science Foundation of China(82002168);National Natural Science Foundation of China(82072308);The 6th Nuclear Energy R&D Project(20201192)

摘要/Abstract

摘要：

疟疾、登革热、寨卡病毒病及流行性乙型脑炎等蚊媒传染病对全球公共卫生造成了严重负担。目前大部分蚊媒传染病预防与控制以媒介蚊虫控制为主。控制媒介蚊虫需要采取综合防制措施，其中生物防制如以控制有害昆虫种群为目的的昆虫不育技术，因其特异性强、安全有效、绿色环保，将成为蚊媒综合防制措施的重要组成部分。释放高质量的绝育雄虫是昆虫不育技术成功的关键保障之一，而集约化生产操作、诱导雄虫绝育的辐照，均会影响绝育雄虫的质量。蚊虫肠道内栖息着大量微生物，这些微生物在宿主的生长发育、抵御侵害、免疫调控等方面发挥着重要作用。该文综述了蚊虫肠道微生物的种类和功能，分析了肠道微生物与绝育雄蚊“致弱”的潜在关系，并展望肠道微生物在昆虫不育技术中控制蚊虫的应用前景，即利用蚊虫肠道微生物群来减缓或修复绝育雄蚊的“致弱”，从而提升昆虫不育技术控制蚊媒的效率。

关键词: 蚊虫肠道微生物, 昆虫不育技术, 辐照, 绝育雄蚊, 致弱

Abstract:

Abstract: Mosquito-borne diseases such as malaria, dengue, Zika and Japanese encephalitis have imposed a severe burden on global public health. Mosquito control remains the main remedy to prevent and control mosquito-borne diseases. Mosquito control requires comprehensive measures; biological control, such as the sterile insect technique (SIT) which aims at suppressing pest population size, will become one of its most important components due to its species-specificity, safety, effectiveness, and environmental-friendliness. The release of high-quality sterile males is one of the key factors for the success of SIT, while intensive mass rearing and irradiation-induced sterility of male mosquitoes will affect sterile males qualities. Mosquito guts are inhabited by numerous microbes that play important roles in the growth and development, invasion resistance, and immune regulation of the hosts. In this article, we review the species and roles of mosquito gut microbiotas, analyze the potential relationship between gut microbiotas and weakening of sterile male mosquitoes. We also investigate the application prospects of gut microbiotas in SIT-based mosquito control, i.e., improving the efficacy of SIT-based mosquito control by reducing or repairing the weakening of sterile male mosquitoes through mosquito gut microbiotas.

Key words: Mosquito gut microbe, Sterile insect technique, Irradiation, Sterile male, Weakness

中图分类号:

S476
R384.1

地里努尔·帕尔汗德, 郑小英, 吴忠道, 潘文杰, 张东京. 蚊虫肠道微生物在辐照不育技术中的应用前景[J]. 中国媒介生物学及控制杂志, 2023, 34(4): 579-584.

Dilinuer PAERHANDE, Xiao-ying ZHENG, Zhong-dao WU, Wen-jie PAN, Dong-jing ZHANG. Application prospect of mosquito gut microbiotas in the irradiation-based sterile insect technique[J]. Chinese Journal of Vector Biology and Control, 2023, 34(4): 579-584.

图/表 1

参考文献 43

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蚊虫肠道微生物在辐照不育技术中的应用前景

Application prospect of mosquito gut microbiotas in the irradiation-based sterile insect technique

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