关键词: 卫生用农药, 成蚊, 抗药性, 健康风险评估, 白纹伊蚊, 埃及伊蚊, 淡色库蚊

Abstract: Objective To explore the health risk assessment for operators and residents using public health pesticides with developed resistance. Methods This paper refers to WHO's Generic risk assessment model for indoor residual spraying insecticides in 2018, attempts to conduct a preliminary health risk assessment based on 4 pesticidal active ingredients (beta-cypermethrin, alpha-cypermethrin, deltamethrin and permethrin), 3 types of formulation and 8 commercial products registered in China, and try to carry out their resistance health risk assessment. Results Most of risk levels to health are basically acceptable when adult Aedes albopictus, Ae. aegypti, and Culex pipiens pallens mosquitoes develop low levels of resistance to pyrethroids. Under high resistance ratios (50-fold for operators, 20-fold for residents) in these species, however, most risk levels to health are not acceptable. Conclusion The research and results are helpful to expand the study field of mosquito resistance and health risk assessment and analysis of influencing factors,so as to ensure the health and safety of operators and residents. It is necessary to strengthen resistance monitoring, improve pesticide usage, promote health risk assessment in integrated vector management.

Key words: Public health pesticide, Adult mosquito, Pesticide resistance, Health risk assessment, Aedes albopictus, Aedes aegypti, Culex pipiens pallens