关键词: 莱姆病, 血清标本, 抗体检测, 关节炎

Abstract: Objective To investigate the infection status in arthritis patients with Lyme disease in Miyun district, and to provide scientific basis for the prevention and treatment of Lyme disease. Methods Serum samples of patients with arthritis were collected, Lyme disease antibody screening in serum samples were detected by enzyme-linked immunosorbent assay, and positive serum samples were identified by western blot. Results A total of 140 serum samples were collected, 17 samples were positive of Lyme disease antibody, the total positive rate was 12.14%. Four serum samples were positive for Lyme disease IgM antibody, the positive rate was 2.86%, 13 serum samples were positive for Lyme disease IgG antibody, the positive rate was 9.29%. The total positive rate of antibody was higher in women than men, and the total positive rate of antibody was highest in 50- years old age group, there were no significant differences in total positive rate between different districts. Conclusion There were patients with arthritis caused by the Borrelia burgdorferi infection in Miyun district, so clinicians should consider Lyme disease in the diagnosis and treatment of arthritis patients.

Key words: Lyme disease, Serum samples, Antibody detection, Arthritis