北京市北部山区恙虫病血清流行病学调查分析

doi:10.11853/j.issn.1003.8280.2016.06.020

摘要/Abstract

摘要：

目的了解北京市北部山区人群恙虫病东方体感染状况及其分布特点，为科学防制恙虫病提供依据。方法于2011年4-8月选取549人开展恙虫病血清流行病学调查，采用ELISA法检测恙虫病IgG抗体，比较不同地区、年龄和性别人群的感染情况，并进行问卷调查。结果共采集人群血清标本549份，恙虫病东方体IgG抗体阳性率为9.47%（52/549）；其中男女性恙虫病血清阳性率分别为11.06%（26/235）和8.28%（26/314）；大城子、太师屯、西田各庄、古北口和石城镇人群血清恙虫病东方体IgG抗体阳性率分别为10.00%、9.33%、15.00%、5.00%和8.08%；不同地区、年龄和性别人群间恙虫病感染率差异无统计学意义（χ²=6.156、6.307、1.215，P=0.188、0.177、0.270）。问卷调查发现仅8人听说过恙虫病；104人认识恙螨，41人在周围环境中发现恙螨；居民主要通过电视获得恙虫病相关知识。结论北京市北部山区人群中存在恙虫病感染，地区分布广泛，可能为恙虫病自然疫源地；暴露人群恙虫病相关知识匮乏，感染风险大，在当地应采用多种形式开展健康教育。

关键词: 恙虫病, 血清学, 北京, 山区

Abstract:

Objective To explore the infection status and the characteristics of distribution of Orientia tsutsugamushi in the north mountainous area of Beijing, and to provide a scientific basis for its prevention and treatment. Methods A total of 549 subjects were selected to carry out the seroepidemiological investigation from April to August of 2011, enzyme-linked immunosorbent assay test(ELISA) method was used to detect the scrub typhus IgG antibody. Meanwhile, in accordance with different geographical region, different age and different sex, the antibody level of the serum samples were made a comparison, and the survey questionnaire was carried out. Results A total of 549 serum samples were collected, the positive rate of scrub typhus IgG antibody was 9.47%. The positive rates of the male and female antibody were 11.06% (26/235)and 8.28%(26/314), respectively. The positive rate of scrub typhus IgG antibody in each monitoring point were Dachengzi 10.00%, Taishitun 9.33%, Xitiangezhuang 15.00%, Gubeikou town 5.00%, Shicheng town 8.08%, respectively. And there were no significant differences in antibody levels of human serum samples in different regions, age and sex groups(χ²=6.156, 6.307, 1.215, P=0.188, 0.177, 0.270). The survey found that only 8 persons knew of scrub typhus, 104 of them could recognize the chigger, and only 41 of them had an obvious chigger bite history. People knew scrub typhus through TV. Conclusion Orientia tsutsugamushi is in endemic in the north mountainous area of Beijing, and the distribution of the regions is wide. Natural foci of scrub typhus likely exist in the north mountainous area of Beijing; and the exposed populations lack of knowledge of scrub typhus and have high infection risk, so it is urgent to take the health education in rural area by various ways.

Key words: Scrub typhus, Serology, Beijing, Mountain area

中图分类号:

R376⁺.2

陈永亮, 杨育松, 贾丽丽, 窦相峰, 吕燕宁, 耿利彬, 王娅琼, 郑钫华, 王化勇. 北京市北部山区恙虫病血清流行病学调查分析[J]. 中国媒介生物学及控制杂志, 2016, 27(6): 597-599.

CHEN Yong-liang, YANG Yu-song, JIA Li-li, DOU Xiang-feng, LYU Yan-ning, GENG Li-bin, WANG Ya-qiong, ZHENG Fang-hua, WANG Hua-yong. Seroprevalence of scrub typhus in the north mountainous area of Beijing[J]. Chines Journal of Vector Biology and Control, 2016, 27(6): 597-599.

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