细胞色素P450在家蝇抗药性中的作用

doi:10.11853/j.issn.1003.4692.2014.06.032

中国媒介生物学及控制杂志 ›› 2014, Vol. 25 ›› Issue (6): 591-593.DOI: 10.11853/j.issn.1003.4692.2014.06.032

细胞色素P450在家蝇抗药性中的作用

邱星辉

中国科学院动物研究所, 农业虫害鼠害综合治理研究国家重点实验室, 北京 100080

收稿日期:2014-07-21 出版日期:2014-12-20 发布日期:2014-12-20
作者简介:邱星辉,男,博士,研究员,主要从事药剂毒理学与昆虫分子生物学研究,Email: qiuxh@ioz.ac.cn
基金资助:
北京市自然科学基金(5142014);国家自然科学基金(31172160)

Roles of cytochrome P450s in insecticide resistance in the house fly, Musca domestica

QIU Xing-hui

State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing 100080, China

Received:2014-07-21 Online:2014-12-20 Published:2014-12-20
Supported by:
Supported by the Natural Science Foundation of Beijing (No. 5142014) and National Natural Science Foundation of China (No. 31172160)

摘要/Abstract

摘要：

细胞色素P450是几乎存在于所有生物体中的一类重要的酶,已知在昆虫对杀虫剂的代谢解毒过程中发挥着非常重要的作用。细胞色素P450对杀虫剂解毒作用的增强是导致昆虫对杀虫剂产生抗药性的普遍而重要的机制。该文综述了有关家蝇细胞色素P450研究的一些重要进展,着重介绍家蝇抗药性相关的细胞色素P450以及细胞色素P450在一些相对新的杀虫剂抗性中的作用。

关键词: 细胞色素P450, 家蝇, 杀虫剂抗性

Abstract:

Insect cytochrome P450s are well known to play an important role in the process of insecticide detoxification. Enhanced detoxification of insecticides is a common mechanism responsible for the development of resistance to various insecticides in insects. This article introduces the current advances in the study of insecticide resistance-associated cytochrome P450s and the potential involvement of cytochrome P450s in the resistance to relatively new insecticides in the house fly (Musca domestica).

Key words: Cytochrome P450, Musca domestica, Insecticide resistance

中图分类号:

邱星辉. 细胞色素P450在家蝇抗药性中的作用[J]. 中国媒介生物学及控制杂志, 2014, 25(6): 591-593.

QIU Xing-hui. Roles of cytochrome P450s in insecticide resistance in the house fly, Musca domestica[J]. Chines Journal of Vector Biology and Control, 2014, 25(6): 591-593.

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细胞色素P450在家蝇抗药性中的作用

Roles of cytochrome P450s in insecticide resistance in the house fly, Musca domestica

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