家蝇金属硫蛋白的研究进展

doi:10.11853/j.issn.1003.4692.2014.04.030

中国媒介生物学及控制杂志 ›› 2014, Vol. 25 ›› Issue (4): 382-384.DOI: 10.11853/j.issn.1003.4692.2014.04.030

• 综述 • 上一篇

家蝇金属硫蛋白的研究进展

赵志刚^1,2,霍新北^1,2,王学军^1,2,康殿民¹,景晓^1,2,赖世宏¹,张世水¹,曲宝泉¹

1 山东大学预防医学研究院,山东省疾病预防控制中心,济南250014;
2 山东省传染病预防控制重点实验室,济南250014

收稿日期:2014-02-26 出版日期:2014-08-20 发布日期:2014-08-20
作者简介:赵志刚,男,硕士,主管技师,从事病媒生物监测及控制研究,Email: zhgzh1982@163.com
基金资助:
山东省医药卫生科技发展计划项目(2009HW055)

Research advances in metallothionein inMusca domestica

ZHAO Zhi-gang^1,2, HUO Xin-bei^1,2, WANG Xue-jun^1,2, KANG Dian-min¹, JING Xiao^1,2,LAI Shi-hong¹, ZHANG Shi-shui¹, QU Bao-quan¹

1 Shandong Center for Disease Control and Prevention,Institute for Preventive Medicine of Shandong University,Jinan250014,Shandong Province, China;
2 The Key Laboratory for Infectious Diseases Prevention and Control in Shandong Province,Jinan250014,Shandong Province, China

Received:2014-02-26 Online:2014-08-20 Published:2014-08-20
Supported by:
Supported by the Development of Medical Science and Technology Project of Shandong Province(No. 2009HW055)

摘要/Abstract

摘要： 金属硫蛋白(MT)是一类广泛存在于生物体内的金属结合蛋白,富含半胱氨酸的小分子蛋白,能螯合多种金属离子,因其功能独特,近年来对MT各方面的研究日益受到重视。该文简述了家蝇MT的结构特点、理化性质和分布情况,以及参与体内解毒、清除自由基和微量元素代谢功能的研究现状及进展。

关键词: 金属硫蛋白, 家蝇, 功能, 研究进展

Abstract: Metallothioneins (MT) are a class of cysteine-rich, low-molecular-weight metal-binding proteins widely distributed in organisms, which can chelate various metal ions. In recent years, MT has been increasingly studied in different aspects due to its special functions. This paper briefly describes the structural characteristics, physical and chemical properties, and distribution ofMT and reviews the research advances in its participation in detoxication, free radical scavenging, and trace element metabolism.

Key words: Metallothionein, Musca domestica, Function, Research advance

中图分类号:

赵志刚,霍新北,王学军,康殿民,景晓,赖世宏,张世水,曲宝泉. 家蝇金属硫蛋白的研究进展[J]. 中国媒介生物学及控制杂志, 2014, 25(4): 382-384.

ZHAO Zhi-gang, HUO Xin-bei, WANG Xue-jun, KANG Dian-min, JING Xiao,LAI Shi-hong, ZHANG Shi-shui, QU Bao-quan. Research advances in metallothionein inMusca domestica[J]. Chines Journal of Vector Biology and Control, 2014, 25(4): 382-384.

参考文献

[1] Dziegiel P,Jelen M,Muszczynska B,et al. Role of metallothionein expression in non-small cell lung carcinomas[J] . Rocz Akad Med Bialymst,2004,49 Suppl 1:S43-45.
[2] Chen M,Zhao C,Chen W,et al. Sensitive electrochemical immunoassay of metallothionein-3 based on K3[Fe(CN)6] as aredox-active signal and C-dots/Nafion film for antibody immobilization [J] . Analyst,2013,138(24):7341-7346.
[3] Kawakami T,Nishiyama K,Kadota Y,et al. Cadmium modulates adipocyte functions in metallothionein-null mice[J] . Toxicol ApplPharmacol,2013,272(3):625-636.
[4] Jung HS,Lim KS,Kim MJ,et al. Hypoxic resistance of hypodermically transplanted pancreatic islets by using cell -absorbable antioxidant Tat-metallothionein[J] . J Control Release,2013,172(3):1092-1101.
[5] Sato S,Shirakawa H,Tomita S,et al. The aryl hydrocarbon receptor and glucocorticoid receptor interact to activate humanmetallothionein 2A[J] . Toxicol Appl Pharmacol,2013,273(1):90-99.
[6] Kagi JH,Kojima Y. Metallothionein:an exceptional metal thiolate protein[J] . Ciba Found Symp,1979(72):223-237.
[7] Cai L,Cherian MG,Iskander S,et al. Metallothionein induction in human CNS in vitro:neuroprotection from ionizing radiation[J] .Radiat Biol,2000,76(7):1009-1017.
[8] Kasai T,Watanabe H,Mori K. Synthesis of the enantiomers of lasiol,an acyclic monoterpene alcohol in the mandibular glandsecretion of the male ants,Lasius meridionalis[J] . Bioorg Med Chem,1993,1(1):67-70.
[9] Miura N,Ashimori A,Takeuchi A,et al. Mechanisms of cadmium-induced chronotoxicity in mice[J] . J Toxicol Sci,2013,38(6):947-957.
[10] Bin BH,Fukada T,Hosaka T,et al. Biochemical characterization of human ZIP13 protein:a homo-dimerized zinc transporter involved in the spondylocheiro dysplastic Ehlers-Danlos syndrome[J] . Biol Chem,2011,286(46):40255-40265.
[11] Tian ZQ,Xu YZ,Zhang YF,et al. Effects of metallothionein-3 and metallothionein-1E gene transfection on proliferation,cell cycle,and apoptosis of esophageal cancer cells[J] . Genet Mol Res,2013,12(4):4595-4603.
[12] Filipiak M,Tylko G,Pyza E. Zinc induces caspase-dependent mitochondrial pathway of the programmed cell death in haemocytesofDrosophila melanogaster[J] . Biometals,2012,25(3):507-516.
[13] Shuja RN,Taimuri SU,Shakoori FR,et al. Efficient expression of truncated recombinant cadmium-metallothionein gene of a ciliate,Tetrahymena tropicalis lahorensis inEscherichia coli[J] . Mol Biol Rep,2013,40(12):7061-7068.
[14] Higashimoto M,Isoyama N,Ishibashi S,et al. Preventive effects of metallothionein against DNA and lipid metabolic damages indyslipidemic mice under repeated mild stress[J] . J Med Invest,2013,60(3/4):240-248.
[15] Lim KS,Lim MH,Won YW,et al. Dual-mode enhancement of metallothionein protein with cell transduction and retention peptidefusion [J] . J Control Release,2013,171(2):193-200.
[16] Atanesyan L,Günther V,Celniker SE,et al. Characterization of MtnE,the fifth metallothionein member in Drosophila[J] . J Biol Inorg Chem,2011,16(7):1047-1056.
[17] Dai S,Yin Z,Yuan G,et al. Quantification of metallothionein on the liver and kidney of rats by subchronic lead andcadmium in combination[J] . Environ Toxicol Pharmacol,2013,36(3):1207-1216.
[18] Loebus J,Leitenmaier B,Meissner D,et al. The major function of a metallothionein from the aquatic fungus Heliscus lugdunensis is cadmium detoxification[J] . J Inorg Biochem,2013,127:253-260.
[19] Shen SF,Wang RL,Lu L,et al. Effect of intravenously injected zinc on tissue zinc and metallothionein gene expression ofbroilers[J] . Br Poult Sci,2013,54(3):381-390.
[20] Sha K,Conner WC,Choi DY,et al. Characterization,expression,and evolutionary aspects of Corazonin neuropeptide and its receptor from the house fly,Musca domestica(Diptera:Muscidae)[J] . Gene,2012,497(2):191-199.
[21] Kraemer LD,Campbell PG,Hare L. Seasonal variations in hepatic Cd and Cu concentrations and in the sub-cellular distribution of these metals in juvenile yellow perch (Perca flavescens)[J] .Environ Pollut,2006,142(2):313-325.
[22] Croteau MN,Hare L,Campbell PG,et al. Metallothionein-like metal-binding protein in the biomonitor Chaoborus:occurrence andrelationship to ambient metal concentrations in lakes[J] . Environ Toxicol Chem,2002,21(4):737-741.
[23] 江泉观.基础毒理学[M] .北京:化学工业出版社,1991:93-94.
[24] 张春阳,曲卫,石勇栓,等. 金属硫蛋白对糖尿病大鼠肾脏氧化应激的影响[J] .第二军医大学学报,2007,28(4):389-392.
[25] 游思湘,李丽立,刘湘新,等. 金属硫蛋白对应激猪血液和肌肉中非酯化脂肪酸及肌乳酸含量的影响[J] . 中国兽医杂志,2011,47(6):9-11.
[26] 张彬,谭琼,肖兵南,等. 外源性金属硫蛋白对奶牛泌乳性能和抗氧化状况的影响[J] .草业学报,2009,18(6):137-143.
[27] 杨沐,李丽立,张彬,等. 外源性金属硫蛋白对奶牛泌乳性能的影响[J] .中国奶牛,2011(10):9-12.
[28] 李砥,龚建福,刘继文. 金属硫蛋白提取液配方对镉中毒小鼠血液脂质过氧化的影响[J] . 新疆医科大学学报,2009,32(5):558-561.
[29] 杨自军,王哲,王宝艾,等. 锌对鸡的毒性及其对鸡体内金属硫蛋白的影响[J] .畜牧与兽医,2004,36(1):20-22.

家蝇金属硫蛋白的研究进展

Research advances in metallothionein inMusca domestica

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

本文评价

[1]	周长印, 关晴晴, 戴雨琪, 刘洪霞, 钱坤. 淡色库蚊保幼激素受体基因CpMet的表达特性和功能分析[J]. 中国媒介生物学及控制杂志, 2021, 32(6): 680-685.
[2]	陈晓敏, 刘芹, 周良才, 吴丽群, 包继永, 吴太平. 武汉市2009－2015年家蝇对常用杀虫剂的抗药性调查[J]. 中国媒介生物学及控制杂志, 2021, 32(4): 468-471.
[3]	孙燕群, 张守刚, 赵姗姗, 陆墨原, 张艳, 王冲, 李成国. 机器学习在蚊虫及蚊媒传染病研究中的应用进展[J]. 中国媒介生物学及控制杂志, 2021, 32(4): 503-508.
[4]	孔庆鑫, 韦凌娅, 沈林海, 王英红, 曹阳. 双链RNA饲喂干扰家蝇CYP6D1基因表达方法的建立[J]. 中国媒介生物学及控制杂志, 2020, 31(4): 430-432.
[5]	常锐锐, 陈海敏, 陈宏敏, 万晴, 乐倩倩, 张瑞玲, 张忠. 家蝇幼虫肠道可培养非厌氧细菌对家蝇成虫取食及产卵的影响[J]. 中国媒介生物学及控制杂志, 2020, 31(3): 294-299.
[6]	刘洪霞, 冷培恩, 刘曜, 吴寰宇. 上海地区2015-2019年白纹伊蚊和家蝇的抗药性发展动态[J]. 中国媒介生物学及控制杂志, 2020, 31(2): 137-142.
[7]	王飞, 蒋璐, 黄慧嫦, 刘洪霞, 陈道湧. 上海市虹口区2015-2019年重要病媒生物对常用杀虫剂的抗药性调查[J]. 中国媒介生物学及控制杂志, 2020, 31(2): 143-147.
[8]	万晴, 黄振东, 薛志静, 乐倩倩, 张瑞玲, 张忠. 家蝇幼虫肠道细菌拮抗球孢白僵菌菌株的筛选[J]. 中国媒介生物学及控制杂志, 2020, 31(1): 36-40.
[9]	王丹, 陈仲权, 罗灿美, 糜娇妮, 田珍灶, 梁文琴. 贵州省毕节和福泉市2018年家蝇抗药性调查[J]. 中国媒介生物学及控制杂志, 2019, 30(6): 618-620.
[10]	万晴, 宋暖, 黄振东, 薛志静, 庄桂芬, 张瑞玲, 许永玉, 张忠. 盐酸环丙沙星对家蝇幼虫和蛹能量物质含量的影响[J]. 中国媒介生物学及控制杂志, 2019, 30(5): 514-518.
[11]	宋暖, 黄振东, 薛志静, 万晴, 庄桂芬, 张瑞玲, 许永玉, 张忠. 喂食盐酸环丙沙星对家蝇生长发育和种群繁殖的影响[J]. 中国媒介生物学及控制杂志, 2019, 30(3): 300-305.
[12]	邓泽静, 倪朝荣, 李万仓, 陈珞洛, 朱子福, 倪庆翔, 林献丹. 浙江省温州市家蝇对5种常用杀虫剂的抗药性调查[J]. 中国媒介生物学及控制杂志, 2019, 30(3): 334-336.
[13]	亓云鹏, 富小飞, 查亦薇, 向泽林, 周晚玲, 侯志刚, 顾伟玲. 浙江省嘉兴市主要病媒生物对常用卫生杀虫剂的抗药性调查[J]. 中国媒介生物学及控制杂志, 2019, 30(3): 337-340.
[14]	马玉涛. 天津市津南区家蝇对常用卫生杀虫剂的抗药性研究[J]. 中国媒介生物学及控制杂志, 2019, 30(2): 221-223.
[15]	马卓, 周小洁, 李静, 李秋红, 刘婷, 曾晓芃. 北京地区2017年家蝇种群对6种常用杀虫剂的抗药性调查[J]. 中国媒介生物学及控制杂志, 2019, 30(1): 69-71.