关键词: 中华按蚊, 溴氰菊酯, 抗药性, 现场调查

Abstract: Objective To investigate the resistance of Anopheles sinensis to deltamethrin and provide baseline data for proper use of insecticide. Methods The filter paper contact method for adult mosquitoes, as recommended by WHO, was used to determine the time for initial knockdown, knockdown rate, and mortality of An. sinensis, and the levels of resistance were determined based on the discriminating doses. Results For the An. sinensis in Jiangling county, Xiangzhou district, Zaoyang city, Tongcheng county, Tianmen city, Yiling district, Wuxue city, Guangshui city, Zengdu district, Jingshan county, and Enshi city, the time for initial knockdownby deltamethrin was 6, 20, 11, 9, 20, 6, 30, 5, 14, 25, and 23 min, respectively; the knockdown rate caused by deltamethrin at 60 min was 9.62%, 7.69%, 14.55%, 2.11%, 3.00%, 48.94%, 2.80%, 10.78%, 14.00%, 1.00%, and 3.06%, respectively. The mortality of An. sinensis at the discriminating dose of deltamethrin was less than 50.00% in all sampling areas except for Enshi where the mortality was 70.85%. Conclusion The resistance of An. sinensis to deltamethrin in Hubei province was high and the spreading of resistance was rapid. Thus, we should strengthen the monitoring of insecticide resistance and implement strategic dosing of insecticide to achieve better control effect.

Key words: Anopheles sinensis, Deltamethrin, Insecticide resistance, Field investigation