关键词: 钩端螺旋体, 监测, 鼠类

Abstract:

Objective To analyze the distribution and variation of Leptospira in humans and host animals after leptospirosis outbreak and to provide a scientific basis for prevention of leptospirosis. Methods Sera of clinically diagnosed patients and host animals were collected and examined by microscopic agglutination test (MAT). The kidney samples of rodent, frog, pig, and teal as well as the midstream urine samples of cattle were collected; pathogens were isolated from the samples and then cultured, and the strains were identified by MAT. Results Five cases of leptospirosis were reported in Pan'an county from 2009 to 2012. A total of 40 duck sera were examined, and 8 were positive for antibodies against Leptospira, including 6 cases for antibody against strain 56601 and 2 cases for antibody against strain 56608. A total of 439 small mammals were examined, and 14 strains of Leptospira, all of which were strain 56601, were isolated. No Leptospira was detected in the kidney samples collected from 80 duck, 390 frog, 244 pig, and 160 cattle midstream urine samples. Conclusion Leptospira is prevalent in host animals in Pan'an county, and the epidemic strains in foci may change. Surveillance should be enhanced to prevent leptospirosis.

Key words: Leptospira, Surveillance, Rodent