关键词: 鼠疫, 肾综合征出血热, 宿主动物

Abstract:

Objective To investigate the species, distribution, and density of dominant species of rodents and parasitical fleas and the infections of rodents with Yersinia pestis and hantavirus (HV) in Jixian of Tianjin, China, and to provide a basis for effective prevention and control of plague and hemorrhagic fever with renal syndrome (HFRS). Methods Cages were used to capture rodents. The captured rodents and the fleas collected from the rodents were classified and identified, and the density of rodents and flea-carrying rate were calculated. Indirect hemagglutination assay was used to detect the Y. pestis F1 antibody. Polymerase chain reaction was used to identify the specific genes of Y. pestis (fra and pla). Fluorescent antibody technique was used to detect HV antigen in rodent lungs (HFRS Ag). Results From April to September in 2011, 269 rodents (8 species, 7 genera, and 3 families) were captured in Jixian of Tianjin, and the density of rodents was 1.15%; 9 fleas (Monopsyllus anisus) were collected from the rodents; the flea-carrying rate was 3.68%, and the total flea index was 0.055. A total of 188 serum samples of rodents were collected, and no Y. pestis F1 antibody was detected. A total of 247 liver samples of rodents were collected, and the specific genes of Y. pestis were not detected. A total of 89 lung samples of rodents were collected, and HV antigen was detected in one sample, with a positive rate of 1.12%; the HV was confirmed as Seoul virus (SEOV). Conclusion R. norvegicus is the dominant species of rodents in Jixian of Tianjin. Both the rodent density and flea index are lower than the standard precaution level for plague control, and no rodent plague epidemic is found. R. norvegicus is the major host animal of HFRS, from which SEOV is detected.

Key words: Plague, Hemorrhagic fever with renal syndrome, Host animal