关键词: 肾综合征出血热, 流行特征, 监测

Abstract:

Objective To investigate the epidemiological characteristics of hemorrhagic fever with renal syndrome (HFRS) in Hebei province, China in 2011 and analyze the surveillance data and to provide a scientific basis for the control of HFRS. Methods The epidemic data of HFRS were collected. The density and virus-carrying rate of rodents at each surveillance site was recorded. PCR genotyping was performed using the positive lungs of rodents. Results In 2011, 513 cases of HFRS including one death were reported in Hebei province, with an incidence rate of 0.71/10⁵ and a fatality rate of 0.20%. These cases were distributed in 74 counties (cities, districts), mostly in Qinhuangdao city and Tangshan city, in Hebei. The peak seasons were in spring and winter. The percentage of cases occurring from March to June was 42.50%, and 205 cases (30.02%) occurred from October to January of the next year. Of all cases, 364 (70.96%) were aged 20-59 years. The male-to-female ratio was 2.72:1. Peasants amounted for 78.36% of all cases. The rodent density in residential area was 2.04%, and the virus-carrying rate was 7.41%; the rodent density in the field was 0.64%, and the virus-carrying rate was 0. The dominant species of rodents in the residential area and field was Rattus norvegicus. The PCR genotyping using positive lungs showed that all belonged to Rattus type (type Ⅱ). Conclusion Hebei province is a mixed epidemic area of HFRS, mostly of Rattus type. We should enhance comprehensive control of HFRS with an emphasis in the 9 counties (districts) with high incidence of HFRS.

Key words: Hemorrhagic fever with renal syndrome, Epidemiological characteristics, Surveillance