关键词: 肾综合征出血热, 流行趋势, 汉坦病毒, 监测点

Abstract: Objective To investigate the trends of hemorrhagic fever with renal syndrome(HFRS)in its surveillance sites in Qingdao for guiding prevention and control. Methods Case surveillance was conducted through national infectious disease report system. Trap-night method was used for reservoir host surveillance. Hantavirus antigens in lungs of reservoir hosts were identified with indirect immunofluorescence assay. All data over the years were analyzed with descriptive epidemiologic method. Results From the year of first emergence to 2010, the average incidence rates of HFRS in Jiaonan, Jiaozhou and Pingdu were 16.52/105, 12.00/105 and 8.35/105 and death rates were 6.44%, 4.48% and 2.96%, respectively. Autumn-winter seasonal peak was obvious annually. Of all cases the number of cases in autumn and winter was 2.51 times as much as those in spring and summer, the ratio of male to female was 2.88:1. Farmers accounted for 83.04%. 78.09% was 30-60 years old. In residential areas the rodent density was 1.15% and the main species were Mus musculus (45.41%) and Rattus norvegicus (35.51%). In fields the density was 0.82% and the main species were R. rattus (35.02%) and R. norvegicus (33.42%). The Hantavirus antigen-carrying rate of hosts was 1.84%. Conclusion Since the first case the epidemic processes of HFRS in 3 surveillance sites in Qingdao had nearly concurrently gone through the early, the first peak, the steady, the second peak and the slow decline stages. The focuses had changed from the Apodemus type in the early stage to the presently mixed type in which Apodemus type was predominate.

Key words: Hemorrhagic fever with renal syndrome, Epidemiologic trend, Hantavirus, Surveillance site