关键词: 过敏性疾病, 螨特异性抗体, 过敏原, 相关性

Abstract: Objective To study the correlation between mite-specific antibody levels in serum and allergen concentration in house dust samples. Methods Thirty - three patients suffering from allergic asthma, allergic rhinitis, atopic dermatitis and urticaria chronica were included in the study. Their mite-specific antibody levels in serum were graded from 4 to 6. Dust from pillows, quilts, mattresses being used by the allergic patients was collected with vacuum cleaner and conserved in a dedicated box, and used for the detection of allergens with HDM allergen detection kit (Acarex company, Germany) with the levels of mite allergens evaluated according to the colour reactions, which were classified as negative, mild positive, moderate positive and highly positive). Results Seventy-nine samples were all positive, with 19 samples being mild positive (positive rate 24.1%), 20 samples moderate positive (25.3%), 40 samples highly positive (50.6%). It was demonstrated by the chi-square test that there were significant differences in antibody levels and positive rates among the three groups(P<0.05), there being a positive correlation between mite-specific antibodies in serum and allergens in bedrooms of patients with moderate and severe allergies. Conclusion There is a positive correlation between mite-specific antibodies in serum and allergens in bedrooms of patients with moderate and severe allergies. Doctors should instruct patients with allergic disorders to clean their bedrooms and linens properly in order to reduce, even eliminate allergens in their bedrooms for the prevention and control of their allergies.

Key words: Allergic diseases, Mite-specific antibodies, Allergen, Correlation