布尼亚病毒科概述

摘要/Abstract

摘要：

布尼亚病毒科是媒传疾病中重要的病毒科之一,传播媒介囊括了医学节肢动物和啮齿动物,如蚊虫、白蛉、蠓、鼠等,宿主动物为哺乳动物,如人类等。2010年在河南、山东等地出现的“蜱虫叮咬事件”是由蜱作为传播媒介,病原体为新型布尼亚病毒的传染疾病,该病严重者可致多脏器功能衰竭、弥漫性血管内凝血,甚至死亡,病死率高达10%。为给布尼亚病毒所致疾病的检测和防治提供理论依据,现就布尼亚病毒科病毒病原学、所致疾病及感染和免疫应答方面的国内外研究做一综述。

关键词: 布尼亚病毒科, 病原学, 感染, 免疫应答

Abstract:

Bunyaviridae is one of the most important vector-borne viruses which are spread by medical arthropods and rodents including mosquitoes, sandflies, midges, rats and others, with mammals such as the human being as its host. It turned out that the “tick bite event”occurring in Henan, Shandong and other places in 2010 was human infectious diseases caused by a new Bunyaviridae spread by its tick vector. Diseases caused by the virus, if severe enough, may lead to multiple organ failure, disseminated intravascular coagulation and even death with a mortality of about 10%. In the present article, an overview is made of the studies done both at home and abroad on the pathogenicity of Bunyaviridae and the diseases, infections and the immune response associated with the virus to provide a theoretical basis for the detection and prevention of diseases caused by Bunyaviridae.

Key words: Bunyaviridae, Pathogenicity, Infection, Immune response

中图分类号:

R373.3

王颖, 邵柏, 于长友, 方绍庆, 刘明杰, 孙宝杰. 布尼亚病毒科概述[J]. 中国媒介生物学及控制杂志, 2012, 23(2): 182-184.

WANG Ying, SHAO Bai, YU Chang-you, FANG Shao-qing, LIU Ming-jie, SUN Bao-jie. An overview of Bunyaviridae[J]. Chines Journal of Vector Biology and Control, 2012, 23(2): 182-184.

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