中国媒介生物学及控制杂志 ›› 2012, Vol. 23 ›› Issue (2): 166-168.

• 调查研究 • 上一篇    下一篇

南通市区黄胸鼠和褐家鼠凝血酶原时间测定分析

王智泉, 章士军   

  1. 南通市疾病预防控制中心消毒与病媒生物防制科, 江苏南通226007
  • 收稿日期:2011-10-08 出版日期:2012-04-20 发布日期:2012-04-20
  • 作者简介:王智泉(1965-),男,副主任医师,主要从事病媒生物防制工作。Email: wwwww1118@sina.com

Prothrombin time determination of commensal rodents in Nantong city

WANG Zhi-quan, ZHANG Shi-jun   

  1. Nantong Center for Disease Control and Prevention, Nantong 226007, Jiangsu Province, China
  • Received:2011-10-08 Online:2012-04-20 Published:2012-04-20

摘要:

目的 测定和分析南通市黄胸鼠和褐家鼠凝血酶原时间(PT)。方法 PT测定采用仪器法,PT采用国际标准化比值(INR)表示。结果 黄胸鼠、褐家鼠及对照大白鼠的INR平均值分别为0.97、1.40和0.88;方差分析表明,黄胸鼠和褐家鼠之间的差异有统计学意义(t=0.426,P<0.05);褐家鼠和大白鼠之间的差异亦有统计学意义(t=-0.527,P<0.05);黄胸鼠和大白鼠之间差异无统计学意义(t=-0.101,P>0.05)。崇川区与开发区的褐家鼠INR值经成组设计t 检验差异有统计学意义(t=4.026,P<0.01),崇川区与港闸区的黄胸鼠经成组设计t 检验差异无统计学意义(t=0.601,P>0.05)。结论 实验所测得的黄胸鼠及褐家鼠INR值范围分别为0.60~1.92和0.84~2.29,PT值有性别、鼠种、区域间差异。

关键词: 黄胸鼠, 褐家鼠, 凝血酶原时间

Abstract:

Objective To determine the prothrombin time (PT) of commensal rodents in Nantong city. Methods The instrument method was used for the determination of PT, which was expressed by international normalized ratio (INR). Results The average INR of Rattus tanezumi, R. norvegicus and the laboratory rats was 0.97, 1.40 and 0.88 respectively. Statistical analysis showed that there was a significant difference in the INR between R. tanezumi and R. norvegicus(t=0.426, P<0.05), and between R. norvegicus and the laboratory rats(t=-0.527, P<0.05),with no difference in the INR between R. tanezumi and laboratory rats(t=-0.101, P>0.05)found. Also, a significant difference existed in the INR of R. norvegicus from Chongchuan district and those from the development zone(t=4.026, P<0.01), no difference in the index seen in R. tanezumi from Chongchuan district and those from Gangzha district(t=0.601, P>0.05). Conclusion The INR of R. tanezumi and R. norvegicus is 0.60-1.92 and 0.84-2.29 respectively, with a difference in PT value between different genders, species and districts.

Key words: Rattus tanezumi, Rattus norvegicus, Prothrombin time

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