关键词: 布鲁氏菌病, 人群血清抗体, 羊存栏数, 羊血清抗体

Abstract:

Objective To analyze the epidemiological surveillance data on brucellosis in Chaoyang city from 1999 to 2008, infer the possible prevalent strain from the information and identify the major source of infection, providing the basis for prevention and control of brucellosis. Methods Based on epidemiological surveillance, sporadic cases and outbreaks from 1999 to 2008 among the focal population in the key areas and 7 counties of the city, as well as cattle and sheep, were subject to serological tests. The sera samples of the 3 groups were collected for antibody detection. Spearman analysis was conducted to identify the correlation between the annual incidence in humans and the number of cattle and sheep herds，the annual incidence and the antibody positive rate of cattle and sheep sera samples, and the antibody seroprevalence in the focal population and that in cattle and sheep．Results The annual incidence was noticeably correlated with the number of cattle and sheep herds and the seroprevalence in sheep (r=0.779, P<0.01; r=0.816, P<0.01; r=0.857, P<0.01)．Blood culture of the pathogens collected from 18 patients in 2009 revealed 2 strains of type 3 Brucella melitensis. Conclusion Brucella melitensis was the major cause of brucellosis epidemics in Chaoyang city, indicating that sheep should be specifically monitored in prevention and control of brucellosis.

Key words: Brucellosis, Antibody in humans, Sheep herds, Sheep antibody