关键词: 流行性乙型脑炎, 综合监测, 预防与控制

Abstract:

Objective To provide the basis for development of the prevention and control strategies of Japanese encephalitis (JE) by analysis of the comprehensive monitoring data on this condition in Henan province. Methods Excel 2003, SPSS 12.0 and Epi Info 2000 were used to analyze the encephalitic cases in Henan from 1995 to 2008 and the monitoring data on vectors and host animals at Tanghe and Xixian counties, state-level monitoring sites. ELISA assay was conducted for detection of serum JE IgG antibody in the host animals. Results The incidence of JE was downward mobile with periodic fluctuation from 1995 to 2008. 91.75% of the cases were found during July to September, and 79.80% were distributed in the south and southeast regions: Xinyang, Nanyang, Zhumadian, Zhoukou and Luoyang. Children aged 0 to 14 years were the primarily affected group in the province (85.01%), though a noticeably increased portion of those who were ≥15 of age (56.84%) was observed in Luoyang city. 87.31% of the cases had not received vaccination or obscure immunity history. The antibody positive conversion rate reached 50% in pigs one month earlier before the onset peak in humans, and the mosquito density peak was present a fortnight ahead of the onset peak. Conclusion The JE epidemic in Henan may be reduced by strengthening the monitoring of vectors and host animals, improving JE vaccination coverage and carrying out specific control measures for children in the prevalent areas as well as the older group in Luoyang city.

Key words: Japanese encephalitis, Integrated monitoring, Prevention and control