关键词: 黑线姬鼠, 抗凝血灭鼠剂, 溴敌隆, 敏感性

Abstract: Objective To determine the susceptibility of Apodemus agrarius to bromadiolone and provide the base data for the monitoring of its resistance to bromadiolone.Methods The males and females were firstly separated and then divided into groups at random.No-choice feeding tests were carried out with 0.0005% bromadiolone bait at seven different feeding days.The relationship between mortality and feeding days was analyzed by Bliss software.Results There was no significant difference(P_b>0.05,P_LFP50>0.05) between the susceptibility of male and female A.agrarius to bromadiolone.The LFP₅₀ and LFP₉₉ of bromadiolone to A.agrarius were 3.18(2.44-4.14)days and 20.12(8.42-48.06) days respectively.Conclusion The diagnose dose,LFP₉₉ value of bromadiolone to susceptible rodent,was the resistance diagnose criterion recommended by WHO.Accordingly,A.agrarius was still alive after fed on the bait containing 0.0005% bromadiolone for 21 days in Ha'erbin,and then it could be considered to have resistance.