关键词: C型肉毒梭菌毒素, 高原鼠兔, 灭杀效果

Abstract: Objective To study the killing efficiency of one million MLD/ml Type-C Botulinum lyophilized preparation to Ochotona curzoniae. Methods Five plots was selected to test and each area was 3 hm². 0.1% wheat baits were put in two plots randomly, other two-plot for 0.15% and the last one for aqueous agent. Besides, the control was 0.25 hm². Results The density of O.curzoniae was 1071.4 holes/hm² before treatment. The killing efficiency of 0.1% wheat baits and 0.15% wheat baits were 96.7% and 97.4% after treatment for six days, respectively. However, the killing efficiency was also 97.7% in the control plots. It showed that there was no significant difference among them. During the test, there were no no-target animals to be poisoned in test plots and within 500 m of it. It indicated that Type-C Botulinum was safe to some degree, but the safety of the chemicals was still further validated in the long run. Conclusion There is no significant difference between botulinum lyophilized preparation and the same titer aqueous botulinum.