关键词: 印鼠客蚤, 灭蚤, 抗药性

Abstract: Objective To study the insecticide resistance development of in Xenopsylla cheopis after insecticide using for several constantly years. Methods Bioassay of flea contact insecticide effective testing membrane was used to carry out the surveillance. Field population in the insecticide applying areas for plague vectors prevention and control fleas was collected and tested, the flea population from non-insecticide using areas as control. Results Each LC_{50 of X.cheopis to malathion, propoxur, dichlorovos, permethrin, deltamethrin and FENDONA in the constant flea-killing areas was 20.20, 3.75, 0.17, 16.50, 117.00 and 8.65 μg·ai/cm² which was 2.08, 1.66, 1.70, 4.78, 16.32 and 2.94 times higher than that of the un-insecticide applying contrast areas. Conclusion Applying insecticide constantly in plague vector fleas control may lead to flea insecticide resistance. It’s better to know the insecticide susceptibility background when we develop a strategy for plague flea vectors prevention and control.}