关键词: 黄毛鼠, 溴敌隆, 敏感性, 抗药性

Abstract: Objective To determine the susceptibility of Rattus rattoides to bromadiolone and provide base data for R.rattoides resistance to bromadiolone. Methods The males and females were firstly separated and then divided into groups at random. No-choice tests were carried out using 0.0002% bromadiolone bait at five different feeding days. The relationship between mortality and different feeding days were analyzed by Bliss software. Results There was no significant difference (P_b>0.05,P_LFP50>0.05) between male and female _R.rattoides for bromadiolone susceptibility. The LFP line was y=0.52+7.58x. On combination of the sex data, LFP₅₀,LFP₉₉ and their 95% confidence limits were 3.90(3.55-4.28) and 7.90(6.24-10.00) days respectively. Conclusion The revised rodent resistance criterion of WHO was integer of LFP₉₉. According to it, _R.rattoides was still alive after fed on 0.0002% poison bait for 8 days in Zhanjiang, and then it could be considered to have resistance.