中国媒介生物学及控制杂志

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哮喘患者居室内尘螨孳生种类、密度及其与抗原浓度的相关性研究

朱洪1;崔玉宝2;饶朗毓2   

  1. 1海南医学院附属医院检验科 海口571101;2海南医学院
  • 出版日期:2007-10-20 发布日期:2007-10-20

Acarine fauna and correlation between mite density and allergen concentration in house dust samples from asthma patients in the city of Haikou

ZHU Hong; CUI Yu-bao; RAO Lang-yu   

  1. Affiliated Hospital, Hainan Medical College, Haikou 571101, China
  • Online:2007-10-20 Published:2007-10-20

摘要: 目的 调查海口市哮喘患者居室孳生尘螨种类、密度及其与抗原浓度的相关性。方法 采集哮喘患者居室尘样,在光镜下分类、计数,并用ELISA法测定Der P1浓度。结果 制片616张,鉴定出16种螨,其中热带无爪螨占71.75%,屋尘螨占9.25%。哮喘患者居室尘样螨孳生密度和抗原浓度均高于正常对照组,差异均有统计学意义(P<0.01),二者间相关性显著(r=0.716,P<0.01)。结论 热带无爪螨为本地区优势螨种,居室尘螨抗原浓度的检测似可替代活螨计数法评价室内尘螨孳生情况。

关键词: 哮喘, 尘螨, 种类, 孳生密度, DerP1

Abstract: Objective To investigate acarine fauna and correlation between mite density and allergen concentration in dust samples from asthma patients in the city of Haikou.Methods House dust samples were collected from asthma patients, then mites were identified and counted,and were detected for allergen concentrations Der P1.Results A total of 616 slides were made and identified as sixteen species of mites,the percentage of Blomia tropicalis and Dermatophagus pteronyssinus were 71.75% and 9.25%,respectively.The densities and mite allergen concentrations were higher in the samples from asthma patients than those in normal control group with significant difference(P<0.01).The correlation between mite density and allergen concentration was significant, too(r=0.716,P<0.01).Conclusion Blomia tropicalis is dominant in this area,and detection for mite allergen concentrations Der P1 may take place of mite counts to evaluate the mite pollution in house dust.