关键词: 淡色库蚊, 残杀威, 羧酸酯酶, 乙酰胆碱酯酶

Abstract: Objective To study the activity of relationship between esterase,acetylcholinesterase and the resistance to propoxur in the larva of Culex pipiens pallens. Methods WHO bioassay and spectrophotometric method were used. Results A strain from field selected using propoxur in lab for generations with 12.07-fold resistance ratio was abtained,which the parent was 4.77-fold. The difference of esterase activity between sensitive and resistant strain was not significant. Otherwise,the acetylcholinesterase activity between two strains existed significant difference at high concentration (100×10^-6,10×10^-6 and 1×10^-6) propoxur. The inhibiting rate was (93.92±0.65)%,(91.69±0.54)% and (87.03±1.14)% respectively in sensitive strain,and (89.81±0.92)%,(87.41±1.66)% and (83.84±0.36)% respectively in resistant strain. Conclusion Metabolic detoxification induced by esterase play a minor role in propoxur-resistant strain. The insensitive AChE may be the main factor in related to the propoxur resistance.