中国媒介生物学及控制杂志

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2005年河北省肾综合征出血热监测分析

韩占英;张艳波;许永刚;于秋丽;齐顺祥;李琦   

  1. 河北省疾病预防控制中心病毒病防治所 石家庄050021
  • 出版日期:2006-12-20 发布日期:2006-12-20

Analysis for Surveillance of Hemorrhagic Fever with Renal Syndrome in Hebei Province in 2005

HAN Zhan-ying; ZHANG Yan-bo; XU Yong-gang; YU Qiu-li; QI Shun-xiang; LI Qi   

  1. Hebei Center for Disease Control and Prevention, Shijiazhuang 050021, China
  • Online:2006-12-20 Published:2006-12-20

摘要: 目的 分析河北省2005年肾综合征出血热(HFRS)流行特征,对监测数据进行综合分析,为制定防制对策提供科学依据。方法 收集全省HFRS疫情资料,对监测点宿主动物进行监测和人群隐性感染率调查,对阳性鼠肺进行基因分型。结果 2005年河北省共报告HFRS病例1741例,死亡7例,发病率为2.54/10万,病死率为0.40%。病例分布于全省139个县(市、区),主要集中于秦皇岛和唐山市。季节特征呈春峰型,3-6月发病数占全年总发病数的57.96%。以青壮年为主,20~59岁组发病1351例,占发病总数的77.60%;男女之比为2.77∶1;农民发病数占69.50%。居民区鼠密度为1.48%,带病毒率为4.62%;野外鼠密度为0.99%,带病毒率为0.97%。居民区和野外的优势鼠种均为褐家鼠。人群隐性感染率为5.36%。阳性鼠肺进行PCR分型,结果均为家鼠型(Ⅱ型)。结论 河北省HFRS疫区是以家鼠型为主的混合型疫区,应以高发病较集中的8个县(区)为重点,贯彻“灭鼠和免疫并重”的防制策略,科学开展HFRS的综合防制。

关键词: 肾综合征出血热, 流行特征, 监测

Abstract: Objective To investigate the epidemiological characteristics of hemorrhagic fever with renal syndrome(HFRS) in Hebei province in 2005,to analy the data by surveillance and to provide scientific evidence for its control and prevention. Methods The pestilence situation data of HFRS was collected. Host animals of monitoring site were monitored. The recessive infection rate of the crowd was investigated. The genotype of positive lungs of the mice was identified. Results The 1741 cases of HFRS and 7 deathes had been reported in Hebei province in 2005. The morbidity was 2.54/100 000 and the mortality was 0.40. All the cases were distributed in 139 counties (cities,districts) and the main attacked areas were Qinhuangdao city and Tangshan city. Dominant peak was found in spring. Besides,the 57.96 of all the cases occurred from March to June. Young people were the major crowd of the disease,1351 cases were among the age of 20-59,amounting to 77.60,and the ratio of male vs female was 2.77∶1.Peasants amounted for 69.50.The rat density in populated area was 1.48,the hantavirus-carrying rate was 4.62; and which in the open country was 0.99,the hantavirus-carrying rate was 0.97.The predominant species of rats were Rattus norvegicus. The recessive infection rate of the crowd was 5.36.The typing of positive lungs by PCR showed that belonged to rattus type (type Ⅱ). Conclusion Hebei province is a mixed epidemic area and rattus type (type Ⅱ) is the major type. We should place emphasis on the eight counties (districts) with more cases,carry out complex prevention and control strategy scientifically for HFRS.