关键词: 家蝇, 氯氟氰菊酯, 杀虫剂筛选, 抗药性治理

Abstract: Objective The high cyhalothrin resistant Musca domestica strain(Cyh-R) was further selected by deltamethrin and pirimiphos-methyl to study the difference of toxicity and to explore the methods of flies resistance management.Methods(Chy-R) strain was regularly selected with deltamethrin and pirimiphos-methyl by spray method,the former named ZX strain,the later named ZJ strain.(Cyh-R) was selected with no insecticide and normal bred,named ZS strain.The toxicity of the cyhalothrin was tested in generations of different resistant strains every twice after selection with topical application bioassay,to compare the difference with(Cyh-R) strain no-selected.Results The(Cyh-R) strain was 561.9-fold resistant compared with insecticide resistant strains at LD₅₀.The LD₅₀ of ZJ strain from F₂ to F₆ showed declining trend,the resistance factors at LD₅₀ declined from 518.2-fold of F₂ to 110.3-fold of F₄ and to(122.6)-fold of F₆.The LD₅₀ of ZX strain from F₂ to F₈ showed declining firstly and increasing later,the resistance factors at LD₅₀ increased from 217.2-fold of F₄ to(808.0)-fold of F₈.The resistance factors at LD₅₀ of ZS strain declined to 242.3-fold of F₈.Conclusion The high insecticide resistant strain to cyhalothrin was selected with organophosphates,could decline resistant to cyhalothrin.The strain was selected with pyrethroids,could cause resistance elevated higher to cyhalothrin.The strain was selected with no insecticide,could also prohibit resistant development to cyhalothrin,but the ratio of decline was lower than pirimiphos-methyl selected.