关键词: 氯敌鼠钠盐, 布氏田鼠, 急性毒力, 致死中量

Abstract: Objective To determine acute toxicity of chlorophacine-sodium in Brandti's voles(Lasiopodomys brandtii).Methods Brandti's voles were treated with chlorophacine-sodium via gastric tube at concentrations of eight gradients based on its median lethal dose LD₅₀ by modified's Krber's method.Results LD₅₀. of chlorophacine-sodium in Brandti's voles was(5.913 mg/kg) with a standard error of 0.082 mg/kg and 95% confidence limit of 5.913±2.172 mg/kg,without significant difference between male and female voles by χ² test(P>0.05).Conclusion Acute toxicity of chlorophacine-sodium in Brandti's voles reached the highest level according to classification standard for toxic chemicals in mice and could be used as an alternative rodenticide with chronic-toxicity in rat control.