关键词: 流行性乙型脑炎, 发病趋势, 监测

Abstract: Objective To study the prevalent status and epidemic tendency of Japanese encephalitis(JE) in Kaijiang county and to provide scientific base for JE prevention and control. Methods JE Epidemic data from 1960 to 2003 were callected,serology surveillance of JE patient,healthy children and pigs were done from 2002 to 2003 by the reverse passive hemagglutination inhibition test (RPHI). Results Annual average incidence rate was 8.16 per 100 000 in 19602003,fatality rate was 5.68%. August is the peak time of onset. The incidence rate of flat area (8.82 per 100 000) was higher than that of hilly area (6.86 per 100 000) (χ²=20.43,P<0.005). The patients less than 10 years old accounted for 94.51% of total patients. The positive rate of serum antibody in healthy children was 51.97%,of which that of 24 years old children (31.03%) was significantly lower than that of 514 years old children (64.89%) (χ²=16.86,P<0.005). The peak of antibody positive rate of pigs was in July,and antibody positive rates were significantly different (χ²=84.68,P<0.005) every ten days in June and July. The clinical serodiagnosed rate of JE cases was 61.54%. Conclusion Incidence rate significantly differs in every year. It may be corelated with air temperature in the locality,rainfall,mosquito intermediary and immunity level. Strengthening JE vaccine immunization in 10 years old children and raising JE immunization coverage rate for them are the keys for controlling prevalence of JE.