中国媒介生物学及控制杂志

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广州市家栖鼠对第一代抗凝血灭鼠剂抗药性研究

易建荣1;林立丰1;伍任初2;何伯新2;梁练3;段金花1;张世炎3;阴伟雄1   

  1. 1广东省疾病预防控制中心消毒杀虫研究所 广州510300;2广州市爱卫会办公室;3湛江鼠疫防治研究所
  • 出版日期:2004-10-20 发布日期:2004-10-20

Study on the Resistance of Commensal Rodents to Anticoagulant Rodenticide in Guangzhou

YI Jian-rong*; LIN Li-feng; WU Ren-chu; et al   

  1. Center for Diseases Control and Prevention of Guangdong province, Guangzhou 510300, China
  • Online:2004-10-20 Published:2004-10-20

摘要: 目的探讨家栖鼠对抗凝血灭鼠剂的抗药性变化。方法按全国鼠类抗药性监测协作组统一方法,进行无选择性摄毒试验。结果经对广州市所辖9区内捕获的130只褐家鼠、31只黄胸鼠、18只小家鼠进行抗药性监测,其抗性率分别为8.5%、45.2%和27.8%,总平均摄药剂量分别为17.72、278.46和1164.24mg/kg,按家栖鼠抗药性检验标准,黄胸鼠和小家鼠对第一代抗凝血剂杀鼠灵已形成抗药性种群,褐家鼠有抗药性个体产生。结论以黄胸鼠和小家鼠为优势种的场所,要考虑使用第二代抗凝血灭鼠剂;以褐家鼠为主的场所,则可继续使用第一代抗凝血灭鼠剂,但应加强对灭鼠药物的敏感性监测,科学、合理用药。

关键词: 家栖鼠, 抗凝血灭鼠剂, 杀鼠灵, 抗药性, 监测

Abstract: Objective To study the resistance changes to anticoagulant rodenticide in commensal rodents.Methods Test of toxin in taking without selectivity by rodents.Results The rodents Rattus norvegicus(130),R.flavipectus(31) and Mus musculus(18),caught in nine districts of Guangzhou were tested.The resistance rates are 8.5%,45.2% and 27.8%,respectively.The average in taking are 17.72 mg/kg,278.46 mg/kg and 1 164.24 mg/kg,respectively.The result shows that R.flavipectus and M.musculus have showed population resistance to the anticoagulant rodenticide Ⅰand R.norvegicus has showed individual resistance.Conclusion The anticoagulant rodenticide Ⅱ should be used in the areas with dominant R.flavipectus and M.musculus.The anticoagulant rodenticide Ⅰcan be still used but should be used scientifically and properly with more tests of sensitivity.