关键词: 肾综合征出血热, 流行特征, 科学灭鼠

Abstract: Objective To evalute the effective intervention for controlling rodents based on epidemiological methods and the epidemic of Hemorrhagic Fever with Renal Syndrome(HFRS) in Fengxian district.Methods On the basis of the epidemic features of HFRS in Fengxian district in 1986- 1995 and the surveillance results that the HFRS virus reservoirs were found all the five species of rodents including Apodemus agrarius and Rattus norvegicus,the bait with bromadiolone were chose and conducted for the elimination of both wild and domestic rodent.The poison baits should be laid in and around the house as well as in field around the villages and towns at the same time.This rodent control programme was conducted only on old epidemic foci emerged over the period 1980- 1995 and the new foci from then on maintained during the spring and autumn every year in 1996- 2001.Using the measures adopted before 1995,the rodent control was carried out in and around the house but mainly inside the house on non-foci.The densities of rodents were in surveillance in 25 towns including farms all over the district and 300 rat-traps were setted in turn on different places of each village every night.The annual mean densities of rodents were then calculated out.Results The annual mean density of rodents and the annual mean incidence of HFRS in the whole district over the period 1996- 2001 in comparison with 1986- 1995 decreased dramatically for 68.55% and 64.36% respectively.Conclusion It was demonstrated by dynamic observation over six years that the epidemic of HFRS could be effectively controlled by the strategy of rodent control based on epidemiological methods.