中国媒介生物学及控制杂志

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单采血浆还输血细胞供血者中疟疾感染的血清流行病学研究

陈素良1; 赵勇1; 张志坤1; 王德昌2; 李桂银1; 邓金华1; 石磊1; 田万春1   

  1. 1河北省卫生防疫站 保定071000; 2永清县卫生防疫站
  • 出版日期:1997-08-20 发布日期:1997-08-20

Seroepidemiological Study on Malaria Infection among Plasmeghereis Donors

Chen Su-liang Zhao Yong; Zhang Zhi-kun; et al   

  1. Hebei Provincial health and Anti-Epidemic Station,Baoding 071000
  • Online:1997-08-20 Published:1997-08-20

摘要: 目的:调查单采浆是否为疟疾感染的危险因素。方法:采用IFAT法检测疟疾与非疟疾对照血清。结果:疟疾患者IFA阳性率为62.05%,抗体阳性者GMRT为40.27;非疟疾病人IFA阳性率为5.32%,抗体阳性者GMRT为26.11。无论疟疾还是非疟疾对照,男女抗体阳性率无统计学差异。不同年龄人群阳性率以18-49岁组为高。进一步分析,单采浆供血者疟疾IFA阳性率为64.08%,受血者及其他人群疟疾分别为52.63%和40.00%;非疟疾中的单采浆供血者为16.11%,未成年人、受血者和供全血者未发现抗体阳性者,其他成人阳性率仅为1.08%。结论:单采浆是疟疾感染的危险因素,同时证明该地蚊传疟疾已经中断。病后投药和血标本采集早迟,是影响疟疾IFA阳性率的因素。

关键词: 疟疾, 单采浆供血者, 免疫荧光抗体

Abstract: 166 sera for malaria cases and 489 sera for non-malaria population from Hebei province were examined for malaria antibodies by immunofluorescence antibody test (IfAT).Poritivety rates and GMRT were 62.05% and 40.27 for maIaria cases with average 193 days after attack, 5.32% and 26.11 for the controls respectively, and no difference between male and female.Peak of positivety rates in different age groups was l8 to 49 years old which also was peak of plasmapheresis donation-age.Through further analysis for different populations, pesitivety rates were 64.08% for plasmapheresis associated with malaria, 52.63%for recipients, 40.00% for cases without history of plasmapheresis and blood transfusion, 16.ll% for plasmapheresis donors and 1.08% for the non-malaria adults without history of plasmapheresis and blood transfusion.Nobody was positive of malaria antibodies for 8 - l7 years old population, recipients and whole blood donors in non-malaria groups.It was demonstrated that plasmapheresis was a risk factor for malaria infection.The levels of positivety rate were related with the time to take anti-malaria drugs and to take blood speciments after attack.