关键词: 西北地区, 钩端螺旋体, 传染源

Abstract: Objective:Investigate the epidemic of leptospirosis in north-west of Hubei province in 1990'S.Methods:The serum of leptospirosis cases were measured using MAT and Dot-ELISA methods,health population immune level with MAT method.The investigation of the source adopt mouse-clip in the evening,cultivatet rat and pig kidney cortex,separate leptospiroal and identify leptospiroal serum groups.Results:The cases of leptospirosis were few 1990s ago and later the continued outbreaks of leptospirosis were in Zhuxi,Xiangyang and Yicheng and so on in north-west of the Hubei province.All patients(964) accounted for 88.93% in cases of 40 years.The time of outbreak mostly centred on September to October,which prolonged for about one month than that in brief precent areas of all Hubei province.The patient's clinical categories were grippotyphosa type and lung bleed type,which accounted for 70.47% and 21.12% respectively in all patients.The density of mice was 3.62% and mice carrier rate 14.37%.The positive rate of antibody was 41.50% in healthy groups.Conclusions:The leptospiral groups among leptospiral patients were mainly icterohaemorrhagiae.They carried the same groups of source of infection such as pigs and mice.