中国媒介生物学及控制杂志

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山东省沂蒙山区莱姆病自然疫源地调查

刘士礼1; 王丽娟2; 万康林3; 林化权4; 陈志林2; 侯学霞3   

  1. 1 山东省费县卫生防疫站273400;2 山 东省卫生防疫站;3 中国预防医学科学院流行病学微生物学研究所;4 费县马头崖乡卫生院
  • 出版日期:2000-06-20 发布日期:2000-06-20

An Endemic Investigation of Lyme Disease in Yimeng Mountains,Shandong Province

Liu Shili*; Wang Lijuan; Wan Kanglin; et al   

  1. Feixian Health and Anti-Epidemic Station,Shandong Province 273400
  • Online:2000-06-20 Published:2000-06-20

摘要: 目的:调查山东省沂蒙山区莱姆病自然疫源地。方法:1992~1999年设点,用间接免疫荧光抗体试验进行人群莱姆病感染调查;用直接免疫荧光抗体法进行蜱中肠带螺旋体率调查;取鼠的肾脏、膀胱分离病原。结果:沂蒙山区人群莱姆病平均感染率为7.50%,林区人群感染率明显高于非林区人群;该地区蜱类以长角血蜱为优势种,该蜱中肠携带莱姆病螺旋体率为12.0%,从86组长角血蜱培养物中获得2株莱姆病螺旋体。结论:从病原学上证实沂蒙山区为莱姆病自然疫源地。

关键词: 莱姆病, 自然疫源地, 血清学, 蜱, 宿主动物

Abstract: From 1992 to 1999 an endemic investigation of Lyme disease was conducted by means of serological and etiological methods in Yimeng mountains of Shandong province. Of 695 forestry residents,49 residents had a significant antibody titer against Borrelia burgdorferi strain B31.The prevalance rate of Lyme disease was 7.50%. Haemaphysalis longicornis was a prevailing species of Ixodidae in the region.Spirochetes were observed in the midguts of 50 H.longicornis in this area by the direct fluorescence antibody method.The positive rate was 12.0%(6/50).2 strains (TSH1,TSH3) of spirochetes were isolated from H.longicornis.Both TSH1 and TSH3 were positively reacted to McAb H5332 and H9724,but negatively to H6831.It was confirmed that Yimeng mountains of Shandong province was the endemic area of Lyme disease.