关键词: 驱避剂, 库蚊, 伊蚊, 驱避效果, 毒性

Abstract: Objective:effects and toxicity of the new repellent formulation,Quwenfuning,were investigated.Methods:the protection time and protected rate were observed after it was used on the human backhand and arms in the laboratory and field. Its toxicity was tested by using rats and rabbits.Results:it provided the complete protection time of 6.46±2.22h against Aedes albopictus and 7.60±2.19h against Ae.aegypti in laboratory.About 60.0～73.7% and 52.4%～93.7% of the volunteers were　protected against Culex modestus (the higher biting rate) and Cx.pipiens pallens (lower biting rate) in 2h and 6h respectively in fields.Its oral and dermal LD₅₀ were higher than 5000mg/kg and 8000mg/kg respectively in rats,and has no dermal and eye irritancy on rabbits.Conclusions:Quwenfuning has a good repellency against mosquitoes,low acute mammalian toxicity,and also safety for human uses.