中国媒介生物学及控制杂志

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1252例犬伤患者狂犬疫苗免疫效果分析

刘令初; 何志胜; 郑官增   

  1. 浙江省台州市卫生防疫站 临海317000
  • 出版日期:1998-04-20 发布日期:1998-04-20

The Immune Effect Analysis of Rabies Vaccine to 1252 Patients Wounded by Dog

Liu Ling-chu; He Zhi-sheng; Zheng Guan-zeng   

  1. Taizhou Health and Anti-Epidemic Station,Linhai 317000
  • Online:1998-04-20 Published:1998-04-20

摘要: 目的:观察狂犬疫苗的免疫效果。方法:采用间接免疫荧光法,检测犬咬患者狂犬疫苗接种后的血清抗体滴度。结果:共检测1252例,抗体阳转率为93.13%,GMT1∶9.21;各年龄段抗体阳转率为83.70%~100.00%(χ2=6.64,P>0.05),GMT1∶6.09~7.70;男、女性抗体阳转率和GMT分别为88.62%、85.07%(χ2=1.57,P>0.05)和1∶6.44、1∶6.29(u=1.33,P>0.05)。结论:人群对狂犬疫苗的免疫应答效果普遍较佳,6年来未出现本地狂犬病疫情。

关键词: 狂犬病, 疫苗, 免疫效果

Abstract: After the rabies patients were given 5 dosage rabies vaccine 10-20 days,we checked antibody of rabies by the immunofluorescence antibody technigue to make sure the effect of rabies vaccine to prevent rabies.From 1991 to 1996,the 1252 patients wounded by dog were invested.The changing rate of antibody from positive to negative was 93.13%,GMT 1∶9.21.The rate of different age from 83.70% to 100.00%(χ2=6.64,P>0.05),GMT 1∶6.09 to 7.70.The sexual difference as below:of male 88.62%,female 85.07%(χ2=1.57,P>0.05),GMT:male 1∶6.44,female 1∶6.39(u=1.33,P>0.05).We get the conclusion,the immunity of people to rabies vaccinc is generally good,the measurement of rabies antibody is a very important role to control rabies.Since 1991 it was not spread.