Abstract: Objective To investigate the epidemiological characteristics of person, time, and place of dengue fever and their domestic and abroad sources in Guangxi Zhuang Autonomous Region (Guangxi), China from 2016 to 2020, and to provide a scientific basis for the prevention and control of dengue fever in the future. Methods The data on dengue fever in Guangxi from 2016 to 2020 were collected from the notifiable disease reporting system. With Excel 2010 and SPSS 20.0, descriptive epidemiological methods were used to analyze the epidemiological characteristics of imported and local cases of dengue fever in Guangxi in the past five years, and to analyze the source of infection and the epidemic pattern of dengue fever in Guangxi. Results A total of 2 183 dengue cases were reported in Guangxi from 2016 to 2020, with an average incidence of 0.89/100 000. Dengue fever was sporadic during 2016 to 2018, and occurred in outbreaks in 2019 and 2020. The incidence of dengue fever peaked in 2019, accounting for 80.20% of the total reported cases. The male-to-female ratio of imported cases was statistically higher than that of local cases (χ²=5.262, P=0.022).The majority of local cases were between 30 and 39 years old (22.61%) and the majority of imported cases were between 30 and 39 years old (27.94%). The local and imported cases showed similar trends in epidemic seasons, mainly in summer and autumn. The imported cases were mainly from Guangdong province in China (74 cases, 88.10%) and from Cambodia (83 cases, 65.35%). In terms of occupational distribution, domestic and overseas imported cases were mainly household workers and unemployed workers, accounting for 20.78% and 20.47% respectively, while domestic imported cases were mainly farmers (43.03%). Conclusion Dengue fever in Guangxi has an increased trend from sporadic patterns to outbreaks. It is important to strengthen the education on dengue control for key populations during epidemic seasons, to enhance the sensitivity of quarantine at entry and exit ports and the level of diagnosis in medical institutions, and to promptly identify and report cases, which are important for reducing the occurrence and spread of dengue fever.

Key words: Dengue fever, Epidemiological characteristic, Local case, Imported case, Prevention and control

摘要： 目的 了解广西壮族自治区（广西）2016－2020年登革热病例的三间分布、境内外来源等流行特征，为今后登革热防控提供科学依据。方法 收集广西2016－2020年法定传染病报告系统中的登革热病例数据，应用Excel 2010和SPSS 20.0软件整理和分析数据，采用描述流行病学方法比较近5年广西登革热输入病例和本地病例的流行病学特点，分析病例的感染来源及广西登革热的流行规律。结果 2016－2020年广西累计报告登革热病例2 183例，平均发病率为0.89/10万。2016－2018年以散发病例为主，2019、2020年出现暴发疫情，2019年发病达到高峰，报告病例数占总病例数的80.20%。输入病例中男女性别比略高于本地病例，二者差异有统计学意义（χ²=5.262，P=0.022）。本地病例以30～39岁为主（22.61%），输入病例以30～39岁最多（27.94%）。本地病例和输入病例发病时间趋势大致相同，以夏秋季为主。省外输入病例中以广东省为主（74例，88.10%），境外输入病例以柬埔寨为主（83例，65.35%）。在职业分布中，本地病例和境外输入病例都以家务及待业人员为主，占比分别为20.78%和20.47%，境内输入病例以农民为主（43.03%）。结论 广西登革热病例由散发转到暴发趋势增强，要加强重点人群以及登革热流行季节的防控知识宣传和疾病监测，提高出入境口岸检疫的敏感性和医疗机构的诊断水平，及时发现和报告病例，以减少登革热疫情发生和传播。

关键词: 登革热, 流行特征, 本地病例, 输入病例, 预防控制