Abstract: Objective To analyze the epidemiological characteristics of dengue fever in Jiangxi province,China from 2011 to 2019, and to provide a theoretical basis for formulating prevention and control strategies against dengue fever in Jiangxi province. Methods Descriptive epidemiological method was used to analyze the monitoring data of dengue fever in Jiangxi province from 2011 to 2019. The Chi-square test and Mann-Whitney U test were used to compare data differences. Joinpoint software was employed to perform trend analysis. Results From 2011 to 2019, a total of 1 352 cases of dengue fever were reported in Jiangxi province,including 250 (18.49%) imported cases and 1 102 (81.51%) local cases. The imported cases were reported mainly from June to October, while the local cases from August to October. Among all patients,there were 707 male and 645 female patients, with a male-to-female ratio of 1.09:1. The male-to-female ratio in the imported cases (3.24:1) was significantly higher than that in the local cases (0.88:1) (χ²=25.927, P<0.001). The patients were mostly aged between 30 and 69 years, with a median age of 45 years. The imported cases had a significantly younger median age than the local cases (35 vs. 48 years, Z=-10.304, P<0.001). Most of the cases were engaged in farming,housework or unemployment,and commercial service,accounting for 71.97% of the total cases. The difference in occupational distribution between the imported cases and local cases was statistically significant (χ²=716.261, P<0.001). The total cases involved 84 counties or districts in 11 cities with subordinate districts across Jiangxi province,and local cases were reported in 23 counties or districts in 7 cities with subordinate districts. The median time interval from onset to diagnosis was 5 days (interquartile range:3 to 7 days;range:the day of onset to 71 days). The time from onset to diagnosis was longer in the imported cases than in the local cases. Of the 250 imported cases,55 were imported from within China,with the most cases from Guangdong province (67.27%);and 195 were imported from abroad,with the most cases from Cambodia (65.64%). Conclusion The epidemic trend of dengue fever in Jiangxi province is on the rise, imposing an increasing challenge to the prevention and control of dengue fever. Relevant control measures should be strengthened to prevent a wider outbreak.

Key words: Dengue fever, Epidemiological characteristics, Imported case, Local case

摘要： 目的 分析江西省2011－2019年登革热流行特征，为江西省制定登革热防控策略提供理论依据。方法 收集江西省2011－2019年登革热病例监测资料进行描述性流行病学分析，数据差异采用χ²和Mann-Whitney等检验。用Joinpoint软件进行趋势分析。结果 2011－2019年，江西省累计报告1 352例登革热病例，其中输入病例250例（18.49%），本地病例1 102例（81.51%），输入病例主要发生在6－10月，本地病例发生在8－10月。所有病例中男性707例，女性645例，男女性别比为1.09：1，输入病例的男女性别比（3.24：1）高于本地病例的性别比（0.88：1）（χ²=25.927，P<0.001）；年龄中位数为45岁，主要集中在30～69岁，输入病例的年龄中位数（35岁）低于本地病例的年龄中位数（48岁），差异有统计学意义（Z=-10.304，P<0.001）；职业分布以农民、家务及待业、商业服务为主，占全部病例的71.97%，输入病例与本地病例的职业分布差异有统计学意义（χ²=716.261，P<0.001）。病例涉及全省11个设区市的84个县（区），其中7个设区市的23个县（区）报告过本地病例。发病至确诊时间间隔中位数为5 d，四分位数间距为3～7 d，最短为发病当天确诊，最长为71 d，输入病例发病到就诊的时间长于本地病例。250例输入病例中，境内输入55例，以广东省输入病例最多（67.27%）；境外输入195例，柬埔寨（65.64%）是输入病例最多的国家。结论 江西省登革热疫情整体呈上升趋势，防控形势愈发严峻，应加强各项防控措施，防止更大范围的暴发流行。

关键词: 登革热, 流行特征, 输入病例, 本地病例