Abstract: Objective To analyze the data of reported cases of vector-borne diseases (VBDs) in China in 2005-2020, and to investigate the epidemic characteristics and trend of VBDs, challenges in prevention and control, and related coping strategies. Methods The descriptive epidemiological method was used to analyze the data of reported cases of VBDs in China in 2005-2020, and the challenges in prevention and control and related coping strategies were determined based on the epidemic characteristics of VBDs, current policies, and related literature domestic and abroad. Results A total of 905 092 cases of 14 VBDs were reported in China in 2005-2020, among which malaria, scrub typhus, and hemorrhagic fever with renal syndrome (HFRS) accounted for 66.94%, the ten notifiable VBDs accounted for 76.01%. A total of 5 076 death cases were reported, among which the death cases due to Japanese encephalitis (JE), HFRS, severe fever with thrombocytopenia Syndrome (SFTS), and malaria accounted for 93.26%. The incidence of VBDs fluctuated and decreased in 2005-2020. The number of cases showed two significant peaks in 2006 and 2014-2015. The Mann-Kendall trend test showed a significant trend of reduction in JE, malaria, typhus, and leptospirosis (P<0.01) and a significant trend of increase in SFTS and scrub typhus (P<0.01). At the same time, the incidence of VBDs showed marked seasonality with a peak in October. About 2 165 districts/counties reported VBDs annually, mainly in the east of the Heihe-Tengchong line. The Mann-Kendall trend test showed that the number of districts/counties reporting such cases tended to increase with no significance (P=0.367). Over the past 16 years, the number of cases of vector-borne diseases tended to decrease in northeast China, while this number tended to increase in southwest China. Different diseases had different ages of onset, and the peak age of onset of VBDs was 20-44 years. The male population tended to have a higher incidence rate than the female population. Conclusion The number of cases of VBDs tends to decrease with fluctuation in China, but it still remains at a relatively high level, and the epidemic area tends to expand, with continuous increases in the incidence rate or mortality rate of some VBDs. As for the new challenges in the control of VBDs, it is necessary to implement related strategies and measures including the integrated vector management and sustainable vector management, so as to further reduce the morbidity and mortality of VBDs and achieve the targets and goals of Health China and Global Vector Control Strategies.

Key words: Vector-borne diseases, Reported cases, Epidemic trend, Challenges in prevention and control, Coping strategy

摘要： 目的 对我国2005－2020年媒介生物传染病报告病例等数据进行分析研究，明确我国媒介生物传染病流行特点、趋势，探讨其防控挑战，提出应对策略。方法 使用描述性流行病学研究方法分析我国2005－2020年媒介生物传染病报告病例数据，基于媒介生物传染病流行特点，结合现有政策及国内外文献确定我国媒介生物传染病防控面临的挑战，探索应对策略及措施。结果 2005－2020年我国14种媒介生物传染病报告病例总数为905 092例，其中疟疾、恙虫病和肾综合征出血热（HFRS）占66.94%，10种法定报告媒介生物传染病占76.01%（687 970/905 092）。报告死亡病例总数为5 076例，其中流行性乙型脑炎（乙脑）、HFRS、发热伴血小板减少综合征（SFTS）以及疟疾的死亡病例占93.26%。2005－2020年间，全国媒介生物传染病发病呈波动下降趋势。在2006和2014－2015年发病数出现2个明显高峰。经Mann-Kendall趋势检验，乙脑、疟疾、斑疹伤寒和钩体病的发病率下降趋势明显，差异有统计学意义（P<0.01），SFTS和恙虫病的上升趋势明显，差异亦有统计学意义（P<0.01）。同时，媒介生物传染病的发生有明显的季节性，总体发病高峰出现在10月。全国媒介生物传染病年均病例报告区（县）约2 165个，主要分布在黑河-腾冲线以东。经Mann-Kendall趋势检验，病例报告区（县）数呈上升趋势，但差异无统计学意义（P=0.367）。16年来，东北地区媒介生物传染病病例数呈下降趋势，而西南地区的病例数则有所增加。不同疾病的主要发病年龄段不同，总体来看，媒介生物传染病的总发病高峰年龄段在20～44岁，发病率男性高于女性。结论 我国媒介生物传染病报告发病数整体呈波动下降趋势，但仍处于较高水平，且流行区有扩大趋势，尚有疾病发病率或死亡率呈持续上升。针对媒介生物传染病防控新挑战，应切实落实媒介生物综合治理和可持续控制等策略和措施，进一步降低媒介生物传染病发病及死亡，努力实现健康中国和全球病媒控制对策阶段性指标和总体目标。

关键词: 媒介生物传染病, 报告病例, 流行特征, 防控挑战, 应对策略