Abstract: Objective To investigate the epidemic situation of dengue fever in Cambodia, the main source of imported cases to China, and the main influencing factors for imported dengue fever from Cambodia to China, and to help formulate targeted response measures and effectively prevent imported cases from abroad. Methods Dengue fever information in Cambodia from 2011 to 2019 was collected from the official website of the World Health Organization and the official account of Public Health Concerns at Frontier Ports. The information about dengue fever cases imported to China from Cambodia was extracted from the China Information System for Disease Control and Prevention. The number of tourists from China to Cambodia was inquired on the website www.chinaqw.com. Excel 2016 software was used to analyze the trend of dengue fever epidemic in Cambodia, the annual growth rate of the number of tourists from China to Cambodia, and the data on cases of dengue fever imported from Cambodia to China from 2011 to 2019. SPSS 19.0 software was used to perform partial correlation analysis. Results During 2011 to 2019, Cambodia had the highest incidence of dengue fever in 2019. In 2018, the proportion of cases of dengue fever from Cambodia increased sharply among total imported cases in China. In 2019, Cambodia became the main source of China's imported cases. At the same time, the number of Chinese residents visiting Cambodia increased year by year. The partial correlation coefficient between the proportion of dengue fever cases from Cambodia and Cambodia's incidence of dengue fever was 0.880 (P=0.004); the partial correlation coefficient between the proportion of dengue fever cases from Cambodia and the number of tourists to Cambodia was 0.887 (P=0.003). Conclusion The number of cases of dengue fever in Cambodia and the number of tourists from China to Cambodia are important factors affecting the number of imported cases in China. Chinese authorities should pay close attention to the incidence of dengue fever and the number of floating population in neighboring countries with close interactions.

Key words: Dengue fever, Import, Cambodia, Number of tourists

摘要： 目的 了解登革热主要输入来源国疫情发生情况和主要影响因素，有助于制定针对性的应对措施，有效防控疫情从境外输入。方法 通过收集整理2011－2019年世界卫生组织官网及“国境口岸公共卫生关注”公众号中的柬埔寨登革热信息，从中国疾病预防控制信息系统中提取柬埔寨输入我国的登革热病例信息和从中国侨网查询我国赴柬埔寨旅游人数信息，利用Excel 2016软件对2011－2019年柬埔寨登革热的流行趋势、我国赴柬埔寨旅游人数的年增长率以及柬埔寨输入我国的登革热病例信息进行统计；采用SPSS 19.0软件进行偏相关统计分析。结果 在2011－2019年期间，2019年是柬埔寨登革热发病强度最高的年份。2018年由柬埔寨输入的登革热在我国输入性登革热病例中所占比例急剧增加，2019年该国成为我国登革热的主要输入来源国，同时我国居民赴柬埔寨旅游人数逐年增加；柬埔寨输入我国的登革热病例所占比例与柬埔寨登革热发病率的偏相关系数为0.880，且有统计学意义（P=0.004）；柬埔寨输入我国登革热病例所占比例与赴柬埔寨旅游人数的偏相关系数为0.887，且有统计学意义（P=0.003）。结论 柬埔寨登革热的病例数和我国赴柬埔寨旅游人数是影响我国输入病例数量的重要因素，我国应该密切关注交流密切周边国家的登革热流行强度和流动人口数量。

关键词: 登革热, 输入, 柬埔寨, 旅游人数