Abstract: Objective To explore the prevalence and related risk factors of brucellosis in Jiaojiang district, Taizhou, Zhejiang province, China. Methods From 2011 to 2018, sampling was performed in Jiaojiang district in proportion to its population, and serological tests were performed for the high-risk population of brucellosis. The Rose Bengal plate test was used for initial screening, and the diagnosis of positive patients was confirmed by the tube agglutination test. The chi-square test was used to compare the positive rates of Brucella antibodies in the subjects with different monitoring years, sexes, ages, years of exposure, and types of work and in different regions. Results A total of 275 people were monitored, and 15 (5.45%) tested positive for Brucella antibodies. Cattle raising was a risk factor for brucellosis (χ²=12.744, P=0.013). The workers with a service length of 5-10 years had the highest antibody-positive rate (13.89%). A total of 9 147 dairy cows were monitored, and 167 (1.83%) of which tested positive for Brucella antibodies. Conclusion Brucella infection persists in Jiaojiang district, so it is necessary to strengthen the training and promotion of brucellosis prevention and control knowledge for the high-risk population, improve their self-protection awareness, and protect them when raising livestock and processing beef and mutton to reduce the infection rate of brucellosis in this area.

Key words: High-risk population, Brucellosis, Risk factors

摘要： 目的 了解浙江省台州市椒江区布鲁氏菌病（布病）感染情况及相关危险因素。方法 2011-2018年按椒江区人口比例概率抽样，对布病的高危人群进行血清学检测。采用虎红平板凝集试验初筛，阳性者采用试管凝集试验确诊，比较不同监测年限、地区、性别、年龄、接触年限和工种的布鲁氏菌抗体阳性率差异，率的比较采用χ²检验。结果 共检测275人，布鲁氏菌抗体阳性15例，抗体阳性率为5.45%。养牛是感染布病的危险因素，差异有统计学意义（χ²=12.744，P=0.013）。工龄在5~10年的人群阳性率最高，为13.89%。共监测奶牛9 147头，阳性167头，阳性率为1.83%。结论 椒江区布鲁氏菌感染持续存在，应加强职业人群布病防治知识的培训和健康促进工作，提高自我防护意识，在饲养牲畜和加工牛羊肉时做好防护。

关键词: 危险人群, 布鲁氏菌病, 危险因素