Surveillance of hemorrhagic fever with renal syndrome in Tiantai county of Zhejiang province, China, from 1984 to 2018

doi:10.11853/j.issn.1003.8280.2020.02.008

Abstract

Abstract: Objective To investigate the epidemic situation of hemorrhagic fever with renal syndrome (HFRS) and the surveillance data of host animals in Tiantai county of Zhejiang province, China, and to understand the epidemiological characteristics and changing trend of HFRS. Methods Case surveillance data were collected; the case data in 1984-2003 were collected from the epidemic data archives of Tiantai county, and the case data in 2004-2018 were collected from the China Information System for Disease Control and Prevention. As a national surveillance site, Tiantai county carried out host surveillance and data collection according to national requirements. Excel 2010 and SPSS 17.0 softwares were used to perform a descriptive epidemiological analysis of HFRS epidemic data and surveillance data of host animals, and ArcGIS 10.0 software was used to draw the disease map of townships. Results A total of 6 223 HFRS cases were reported in Tiantai county in 1984-2018, with a mean annual incidence rate of 32.36/100 000; the peak of HFRS epidemic was observed in 1986, with an incidence rate of 206.10/100 000, and then the incidence rate of HFRS decreased rapidly; the incidence rate of HFRS remained at a low level in 2001-2018, with a mean annual incidence rate of 7.01/100 000. The onset seasons of HFRS showed two peaks, with a peak in November to next January (44.08%, 2 743/6 223) and a small epidemic peak in April to June (1 369/6 223, 22.00%). Surveillance data showed that 90.92% (5 658/6 223) of the cases were distributed in 8 plain townships/streets at the Shifeng River Coast of Tiantai county. Most patients were male young adults, and the male/female ratio was 1.66:1 (3 884/2 339). Most patients were farmers (5 553/6 223, 89.23%). The mean density of rodents was 8.87% in 1984-2018, and the mean proportion of virus-carrying rodents was 4.49%. Conclusion The overall incidence rate of HFRS tends to decrease in Tiantai county and maintains at a low level in recent years, and the cases are widely but unevenly distributed and have obvious regional characteristics. Tiantai county is a mixed HFRS epidemic area with Apodemus as the main type of host animal, and there are still high rodent density and virus-carrying rate.

Key words: Hemorrhagic fever with renal syndrome, Surveillance, Incidence

摘要： 目的分析浙江省天台县肾综合征出血热（HFRS）疫情及宿主动物监测资料，了解天台县HFRS流行特征和变化趋势。方法收集病例监测数据，其中1984-2003年病例数据来源于天台县疫情资料汇编，2004-2018年病例数据来源于中国疾病预防控制信息系统。天台县作为国家级监测点，宿主监测资料按国家要求开展监测收集。采用Excel 2010、SPSS 17.0软件对HFRS疫情数据和宿主动物监测数据进行描述流行病学分析，采用ArcGIS 10.0软件绘制乡镇发病地图。结果 1984-2018年天台县累计报告HFRS病例6 223例，年平均发病率32.36/10万；流行高峰为1986年，发病率达206.10/10万，之后呈快速下降趋势；2001-2018年维持在较低水平，年平均发病率为7.01/10万。发病季节呈双峰型，每年11月至次年1月为流行高峰，占病例总数的44.08%（2 743/6 223），4-6月为流行小高峰，占22.00%（1 369/6 223）。监测结果显示，90.92%（5 658/6 223）的病例分布在天台县始丰溪沿岸的8个平原乡镇、街道，病例以男性青壮年为主，男女性别比为1.66：1（3 884/2 339），职业以农民为主（5 553/6 223，89.23%）。1984-2018年平均鼠密度为8.87%，鼠带病毒率平均为4.49%。结论天台县HFRS疫情总体呈下降趋势，近年维持在平稳状态，但病例分布广，分布不均衡，呈地域性。该县属于姬鼠型为主的混合型HFRS疫区，鼠密度和带病毒率仍然较高。

关键词: 肾综合征出血热, 监测, 发病率

CLC Number:

R373.3⁺2

PANG Wei-long, ZHENG Xiang, GE Jun-hua, CUI Qing-rong, LIU Ying, HU Ya-fei, SHEN Wei-wei, HU Hai-yan, DING Bin-bin, SUN Ji-min, LIN Hai-jiang. Surveillance of hemorrhagic fever with renal syndrome in Tiantai county of Zhejiang province, China, from 1984 to 2018[J]. Chines Journal of Vector Biology and Control, 2020, 31(2): 158-163.

庞卫龙, 郑翔, 葛君华, 崔清荣, 刘营, 胡雅飞, 沈伟伟, 胡海燕, 丁斌彬, 孙继民, 林海江. 浙江省天台县1984-2018年肾综合征出血热监测分析[J]. 中国媒介生物学及控制杂志, 2020, 31(2): 158-163.

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