An investigation of firstly identified natural foci of hemorrhagic fever with renal syndrome in some areas of Fujian province, China

doi:10.11853/j.issn.1003.8280.2019.06.023

Abstract

Abstract: Objective To investigate the type and range of natural focus of hemorrhagic fever with renal syndrome (HFRS) in Fujian province, China, and to provide a scientific basis for the prevention and control of this disease. Methods An investigation of host animals of HFRS was carried out in 15 surveillance sites between 2009 and 2017. Rodents were captured using cages at night, and the rodent density and constituent ratios were calculated. Immunofluorescent assay was used to detect and identify hantavirus (HV) antigen in rodent lungs. Results The mean rodent density was 7.05% in the 15 surveillance sites, and Rattus norvegicus, which carried Seoul HV, was the dominant species. The mean virus-carrying rate of rodents was 6.27%, and R. norvegicus accounted for 83.78%. The mean virus-carrying index of rodents was 0.07, and Longhai had the highest virus-carrying index of rodents 0.12. HV antigen was detected for the first time from R. norvegicus in the cities or counties of Anxi, Shaxian, Longhai, Zhangpu, Dehua, Wuping, Yunxiao, and Qingliu, and from R. norvegicus and R. tanezumi in the counties of Hua'an, Jiangle, and Mingxi. Conclusion It is confirmed for the first time that there are natural foci of HFRS in the 11 surveillance sites. Rattus norvegicus carrying Seoul HV is the main host animal and source of infection with HFRS. The epidemic area of domestic rodent-type HFRS is spreading to the southern and western areas in Fujian province, and widely distributed.

Key words: Hemorrhagic fever with renal syndrome, Host animal, Natural focus

摘要： 目的掌握福建省肾综合征出血热（HFRS）自然疫源地类型及范围，为防制工作提供科学依据。方法 2009-2017年选择15个监测点进行HFRS宿主动物调查。采用笼夜法捕获鼠形动物，计算鼠密度及构成比，应用免疫荧光法对鼠肺进行汉坦病毒（HV）抗原检测及分型。结果 15个监测点平均鼠密度为7.05%，褐家鼠是主要鼠种，携带汉城型HV（SEOV）；平均鼠带病毒率为6.27%，褐家鼠占83.78%；平均带病毒鼠指数为0.07，龙海市带病毒鼠指数最高为0.12。首次从安溪、沙县、龙海、漳浦、德化、武平、云霄及清流县（市）的褐家鼠中检出HV抗原，从华安、将乐和明溪县的褐家鼠和黄胸鼠中检出HV抗原。结论首次证实11个调查点存在HFRS自然疫源地，主要宿主动物及传染源以褐家鼠为主，携带SEOV。福建省HFRS家鼠型疫区开始向南部及西部地区扩散，疫区分布十分广泛。

关键词: 肾综合征出血热, 宿主动物, 自然疫源地

CLC Number:

R373.3⁺2

CHEN Yang, DENG Yan-qin, LIN Dai-hua, XIAO Fang-zhen, LIN Wen, WANG Jia-xiong, HAN Teng-wei, LIU Jing, LIU Wei-jun. An investigation of firstly identified natural foci of hemorrhagic fever with renal syndrome in some areas of Fujian province, China[J]. Chines Journal of Vector Biology and Control, 2019, 30(6): 692-695.

陈阳, 邓艳琴, 林代华, 肖方震, 林文, 王加熊, 韩腾伟, 刘菁, 刘维俊. 福建省部分地区首次确定肾综合征出血热疫源地的调查研究[J]. 中国媒介生物学及控制杂志, 2019, 30(6): 692-695.

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