Abstract: Objective　To investigate Leptospira serovars in Fujian province, China, and to provide a scientific basis for the prevention and control of leptospirosis. Methods　Five investigation sites were established according to the epidemic situation of this disease. In order to determine the main serovars of Leptospira carried by humans and host animals, Leptospira was cultured with blood, kidney, or urine collected from rats, pigs, and frogs. The level of anti-Leptospira antibody was determined in human and rat sera. Serovars and infection status of Leptospira were analyzed based on these studies. Results　The investigation of hosts showed that the population density of rodents was 5.83% in the open air of the main epidemic area. Main species were Rattus tanezumi, R. losea, and Niviventer fulvescens, which accounted for 29.87%, 28.19%, and 17.11%, respectively. Leptospira was first isolated from N. coxingi in Changtai county. The positive rate of serum antibody in rats was 11.04%. Autumnalis, Australis, and Grippotyphosa were three of the dominant serotypes in rats. The detection rate of serum antibody in humans was 8.25%. Autumnalis, Pyrogenes, Hebdomadis, and Australis were dominant serotypes in humans. Conclusion　The serovars of Leptospira carried by rats and humans are complex in Fujian, which means leptospirosis surveillance should be well performed.

Key words: Leptospirosis, Surveillance, Leptospira serovar

摘要： 目的　掌握福建省钩端螺旋体(钩体)感染菌群,为防治工作提供科学依据。方法　根据全省疫情选取调查点,采集鼠、猪、青蛙的血或肾、尿标本进行钩体培养,采集人、鼠血清测定抗体,分析钩体感染情况和感染菌群。结果　宿主动物调查显示,鼠密度为5.83％,以黄毛鼠、黄胸鼠和针毛鼠为主,分别占29.87% 、28.19%和17.11%,首次从长泰县白腹巨鼠分离出钩体。鼠血清钩体抗体阳性率为11.04%,主要感染菌群为秋季群、澳洲群和流感伤寒群,健康人群钩体抗体阳性率为8.25%,感染菌群以秋季群、致热群、七日热群和澳洲群为主。结论　福建省鼠类和人群感染钩体菌群复杂,应切实做好钩体病的监测工作。

关键词: 钩端螺旋体病, 监测, 感染菌群