Abstract: Objective To investigate the resistance ofRattus tanezumiandR. norvegicusto bromadiolone in Baoshan district of Shanghai, and to provide a guidance rodenticide application.Methods The experiment was performed according to the non-selective feeding method proposed by national rodent resistance cooperation group.Results All the 21 individuals of R. tanezumiand 20 individuals ofR. norvegicusdied in the observation period, after being fed with 0.005% bromadiolone. The average killing days were 6.3 and 6.7 days, respectively. The average consumptions of bromadiolone were 14.91 and 23.99 mg/kg,respectively. Bromadiolone-resistant R. tanezumior R. norvegicusindividual was not detected.Conclusion Rattus tanezumi and R. norvegicusin Baoshan district of Shanghai are not resistant to bromadiolone. Routine monitoring of bromadiolone resistance should be performed. The first- and second-generation anticoagulant rodenticides should be chosen properly to delay the development and evolution of rodenticide resistance in rodents.

Key words: Rattus tanezumi, Rattus norvegicus, Bromadiolone, Rodenticide resistance

摘要： 目的 调查宝山区黄胸鼠和褐家鼠对溴敌隆杀鼠剂的抗药性,为科学使用化学灭鼠药物提供理论依据。方法 按照全国鼠类抗药性监测协作组统一的无选择性摄毒实验方法。结果 实验的21只黄胸鼠和20只褐家鼠,供给0.005%溴敌隆毒饵后在实验期限内均死亡,平均死亡天数分别为6.3和6.7 d,平均消耗溴敌隆原药分别为14.91和23.99 mg/kg,且未检测到抗溴敌隆的黄胸鼠和褐家鼠个体。结论 宝山区的黄胸鼠和褐家鼠对第二代抗凝血杀鼠剂(溴敌隆)均无明显抗药性。应定期开展抗药性监测,科学选用第一、二代抗凝血杀鼠剂,以延缓抗药性的发生和发展。

关键词: 黄胸鼠, 褐家鼠, 溴敌隆, 抗药性