Abstract:

Objective To investigate the resistance of malaria vector Anopheles to five insecticides in Liaoning province, China and to provide a basis for prevention and control strategies. Methods The filter paper contact method for adult mosquitoes, as recommended by WHO, was used to measure the mortality of malaria vector Anopheles and its susceptibility to five insecticides. Results Malaria vector Anopheles had resistance to five insecticides in Donggang city of Dandong and Beizhen city of Jinzhou, and the lowest mortality was only 16.7%. In Dandong, Tieling, and Jinzhou, Anopheles mosquitoes also developed varying degrees of resistance to 4% DDT, 0.05% deltamethrin, and 0.05% beta-cypermethrin, with the highest mortality of 97.4%. The 0.1% propoxur had good lethal effect on malaria vector Anopheles in Zhen'an district of Dandong and Kaiyuan city of Tieling, and 0.75% permethrin had good lethal effect on Anopheles mosquitoes in the Zhen'an district, all leading to a mosquito mortality of 100%. Conclusion In some areas of Liaoning province, malaria vector Anopheles maintains high resistance to DDT, and it also has varying degrees of resistance to beta-cypermethrin and deltamethrin. Thus, it is necessary to properly use the insecticides for delaying the development of insecticide resistance. Malaria vector Anopheles is relatively sensitive to propoxur and permethrin, so the two can be applied as main insecticides for Anopheles control at present.

Key words: Anopheles, Insecticide resistance, Insecticide

摘要：

目的 了解辽宁省媒介按蚊对5种杀虫剂的抗药性,为制定防制策略提供依据。方法 采用WHO成蚊滤纸接触法,观察蚊虫死亡率,测定其对5种杀虫剂的敏感性。结果 丹东东港市及锦州北镇市媒介按蚊对5种杀虫剂均存在抗药性,最低的死亡率仅为16.7%;丹东、铁岭和锦州市媒介按蚊对4%DDT、0.05%溴氰菊酯和0.05%高效氯氰菊酯也产生了不同程度的抗药性,最高死亡率为97.4%;0.1%残杀威对丹东振安区、铁岭开原市媒介按蚊和0.75%氯菊酯对振安区媒介按蚊杀灭效果较好,死亡率均为100%。结论 在辽宁省部分地区媒介按蚊对DDT的抗药性仍然较高,同时对高效氯氰菊酯、溴氰菊酯也形成不同程度抗药性。因此,应合理使用这些药剂,以延缓抗药性的发展;媒介按蚊对残杀威、氯菊酯相对较敏感,可作为现阶段主要的杀虫剂使用。

关键词: 按蚊, 抗药性, 杀虫剂