Analysis of an imported Lyme disease during Beijing Olympics

Chines Journal of Vector Biology and Control ›› 2011, Vol. 22 ›› Issue (2): 175-177.

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Analysis of an imported Lyme disease during Beijing Olympics

HOU Xue-xia¹, BO Tao², LIU Xiao-lin³, GENG Zhen¹, SHI Xiao-yan³, HAO Qin¹, WAN Kang-lin¹

1 State Key Laboratory for Infectious Diseases Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China;
2 Qingdao Public Health Bureau;
3 Qingdao Center for Disease Control and Prevention

Received:2010-09-30 Online:2011-04-20 Published:2011-04-20

北京奥运会期间的一例输入性莱姆病病例分析

侯学霞¹, 薄涛², 刘晓琳³, 耿震¹, 史晓燕³, 郝琴¹, 万康林¹

1 中国疾病预防控制中心传染病预防控制所，传染病预防控制国家重点实验室，北京 102206;
2 山东省青岛市卫生局;
3 青岛市疾病预防控制中心

通讯作者: 万康林，Email: wankanglin@icdc.cn
作者简介:侯学霞(1968-)，女，主管技师，从事莱姆病研究。

Abstract

Abstract:

Objective To analyze the serological Results derived from suspected Lyme Disease patients for efficient diagnosis and treatment. Methods Using the indirect immunofluorescence assay(IFA), enzyme-linked immune sorbent assay (ELISA) and western blot(WB), suspected Lyme Disease patients were tested for Borrelia burgdorferi IgM and IgG antibodies. A comprehensive analysis was conducted in combination with clinical cases. Results IgG antibodies were positive as shown by IFA, ELISA and WB methods. The titer of IgG antibodies was up to 1∶128 as shown in IFA and two protein bands, P83 and P39, were present in WB. IgM antibodies were negative as shown in the three test approaches. Conclusion Based on the typical clinical course and positive laboratory Results of the patients, the diagnosis of Lyme disease can be confirmed.

Key words: Lyme disease, Serology, Indirect immunofluorescence assay test, Enzyme-linked immune sorbent assay

摘要：

目的分析拟诊莱姆病患者血清学检查结果，为有效诊治莱姆病提供科学依据。方法应用间接免疫荧光试验(IFA)、ELISA和蛋白免疫印迹(WB)3种实验方法，对此例患者进行血清抗伯氏疏螺旋体IgM和IgG抗体检查，并结合临床疾患进行综合分析。结果 3种试验方法IgG均为阳性，其中IFA的IgG抗体滴度达到1∶128，WB的IgG有2条蛋白带P83和P39; 3种试验方法IgM均为阴性。结论患者临床发展病程符合莱姆病的特征，实验室结果阳性，莱姆病的诊断可以成立。

关键词: 莱姆病, 血清学, 间接免疫荧光试验, 酶联免疫吸附试验

CLC Number:

R377

HOU Xue-xia, BO Tao, LIU Xiao-lin, GENG Zhen, SHI Xiao-yan, HAO Qin, WAN Kang-lin. Analysis of an imported Lyme disease during Beijing Olympics[J]. Chines Journal of Vector Biology and Control, 2011, 22(2): 175-177.

侯学霞, 薄涛, 刘晓琳, 耿震, 史晓燕, 郝琴, 万康林. 北京奥运会期间的一例输入性莱姆病病例分析[J]. 中国媒介生物学及控制杂志, 2011, 22(2): 175-177.

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Analysis of an imported Lyme disease during Beijing Olympics

北京奥运会期间的一例输入性莱姆病病例分析

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