Abstract:

Objective To identify the relationship between the outbreak of hemorrhagic fever with renal syndrome (HFRS) and the distribution of animal hosts in Chengde city, and provide the corresponding prevention and control strategies. Methods The host animals of HFRS were monitored using night traps. The epidemic data were analyzed using Excel and Epi Info. Results Since the first HFRS case in 1984, serological verification and monitoring of the host animals had been conducted in the city based on the epidemic dynamics. The captured rodent species included Niviventer confucianus, Apodemus agrarius, A. peninsulae, Myodes rufocanus, Rattus norvegicus, Tscherskia triton, Spermophilus dauricus, and Cricetulus barabensis, in which virus-carrying animals were mainly R. norvegicus, A. agrarius, N. confucianus, and A. peninsulae. A. peninsulae was a virus-carrying species first captured in Pingquan county in the fall of 2004, while N. confucianus was first captured in Chengde Summer Resort in 2005. The highest virus-carrying rate appeared in 2002 (8.40%). After 2005, no virus host animals were observed. Conclusion The prevalent HFRS pathogen in Chengdu city was the SEO strain. Strengthening monitoring, immunization and eradication in the city and implementing targeted prevention measures to specific focal populations are crucial to effective prevention and control of the epidemic.

Key words: Hemorrhagic fever with renal syndrome, Epidemiological investigation

摘要：

目的 分析承德市肾综合征出血热(HFRS)疫情发生和动物宿主分布关系，提出防控策略。方法 用夹夜法开展HFRS宿主动物监测，用Excel和Epi Info等统计软件分析疫情资料。结果 承德市自1984年出现HFRS病例后，根据疫情情况开展病例血清学核实和宿主动物监测工作，捕获鼠种包括北社鼠、黑线姬鼠、大林姬鼠、棕背鼠平、褐家鼠、大仓鼠、达乌尔黄鼠、黑线仓鼠等多种小兽，捕获的带病毒鼠种主要有褐家鼠、黑线姬鼠、北社鼠、大林姬鼠。其中大林姬鼠是2004年秋季在平泉县首次发现的带病毒鼠种，北社鼠为2005年首次在承德避暑山庄内发现的带病毒鼠种。鼠带病毒率最高年度为2002年(8.40%)，2005年以后未发现带病毒鼠。结论 承德市仍以家鼠型HFRS为主，加强辖区内的监测、免疫和灭鼠工作，对重点人群采用不同的防治方法，是控制疫情的有效措施。

关键词: 肾综合征出血热, 流行病学调查