关键词: 莱姆病, 流行病学, 莱姆病螺旋体

Abstract:

　　【Abstract】　Objective　To understand the epidemic situation of Lyme disease and its distribution in Qinghai, and to collect the information on main vectors and main host carrying bacterium. Understand the infection level of Lyme disease to human and provide the evidence for the surveillance and control of it. Methods　Lyme disease leptospira were tested by PCR, and blood serum antibody (lgG) were determined by immunfluorescence (IFA). Results　A total of 1108 people were investigated, and 167 cases were positive, the average infection rate was 15.07%. The people’s average infection rate was 7.98% in the forest areas, and  21.21% in the farming. There was significant difference between them (χ2＝36.68, P＜0.001). However, there was no significant difference among different gender and age groups. The main vector was Qinghai blood tick, and the rate carrying bacterium was 23.93%. The main host was the house mouse accounting for 46.08%, which the rate of carrying bacterium was 20.59%. Conclusion　Not only the infection of Lyme disease is higher, but also the infection rate is also higher in the population. The average infection level is higher than nation average level. The infection situation varies greatly in different areas because of the difference of ecologic environment, production manner and living habit. The average infection rate in the farmland is obvious higher than that in pasture areas. Qinghai blood tick is the important vector, and there is a Lyme natural foci in Qinghai.

Key words: Lyme disease, Epidemiology, Borrelia burgdorferi