中国媒介生物学及控制杂志 ›› 2009, Vol. 20 ›› Issue (4): 317-318.

• 论著 • 上一篇    下一篇

广州市斯氏屋顶鼠对第一代抗凝血灭鼠剂抗药性初步研究

易建荣1,段金花1,林立丰1,张世炎2,梁练2,阴伟雄1   

  1. 1 广东省疾病预防控制中心消毒杀虫研究所(广州 510300);2 广东省湛江鼠疫防治研究所
  • 收稿日期:2009-02-25 出版日期:2009-08-20 发布日期:2009-08-20
  • 作者简介:易建荣(1964-),男,主任医师,主要从事病媒生物的防制研究。
  • 基金资助:

    广东省医学科学技术研究基金(A2005092)

Primary study on the resistance of Rattus rattus sladeni to anticoagulant rodenticide in Guangzhou

 YI Jian-Rong, DUAN Jin-Hua, LIN Li-Feng, ZHANG Shi-Yan, LIANG Lian, YIN Wei-Xiong   

  1. Guangdong Center for Disease Control and Prevention, Guangzhou, Guangdong 510300, China
  • Received:2009-02-25 Online:2009-08-20 Published:2009-08-20

摘要:

  【摘要】 目的 探讨斯氏屋顶鼠对抗凝血灭鼠剂的抗药性变化。方法 参照全国鼠类抗药性监测协作组统一方法,进行无选择性摄毒试验。结果 经对广州市所辖9个区内所捕获的53只斯氏屋顶鼠进行抗药性监测,存活率为3.8%,其总平均摄药剂量为30.31 mg/kg,存活平均摄药剂量为58.29 mg/kg。经与同期同地家栖鼠抗药性比较,该鼠种对第一代抗凝血灭鼠剂敏感性介于黄胸鼠与褐家鼠之间。结论 控制斯氏屋顶鼠可使用第一代抗凝血灭鼠剂,但应加强对灭鼠药物的敏感性监测,科学、合理用药。

关键词: 斯氏屋顶鼠, 抗凝血灭鼠剂, 杀鼠灵, 抗药性

Abstract:

  【Abstract】 Objective To study the resistance of Rattus rattus sladeni to anticoagulant rodenticide. Methods No?choice food test was used in this study according to the method of national rodent resistance surveillance group. Results The rodents caught in nine districts of Guangzhou were tested. The survival rate  was 3.8%. The total average dosage was 30.31 mg/kg, and survival  average dosage  was  58.29 mg/kg.  The  result  showed  that  its  sensitivity  to  anticoagulant   rodenticide  was  between R.tanezumi and  R.norvegicus.  Conclusion The  anticoagulant  rodenticide can be still used to the control of R.rattus sladeni. But it should strengthen the resistance surveillance, and the chemicals should be used scientifically and rationally. 

Key words: Rattus rattus sladeni, Anticoagulant rodenticide, Warfarin, Resistance

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