中国媒介生物学及控制杂志 ›› 2011, Vol. 22 ›› Issue (6): 541-542,549.

• 论著 • 上一篇    下一篇

山西省娄烦地区北社鼠对杀鼠灵的敏感性研究

常文英, 郭学林, 宁振东, 王庭林, 邹波, 杨新根, 侯玉, 朱文雅   

  1. 山西省农业科学研究院植物保护研究所,山西太原 030031
  • 收稿日期:2011-03-25 出版日期:2011-12-20 发布日期:2011-12-20
  • 作者简介:常文英(1967-),女,副研究员,主要从事啮齿类动物生态及植物保护研究工作。Email: changwenying@126.com
  • 基金资助:

    山西省科技攻关项目(20090311031,2006031049);山西省国际合作项目(2008081001-5,2007081001);山西省农业科学院攻关项目(YGG0931)

Susceptibility of Niviventer confucianus to warfarin in Loufan, Shanxi

CHANG Wen-ying, GUO Xue-lin, NING Zhen-dong, WANG Ting-lin, ZOU Bo, YANG Xin-gen, HOU Yu, ZHU Wen-ya   

  1. Institute of Plant Protection Shanxi Academy of Agricultural Sciences, Taiyuan 030031, Shanxi Province, China
  • Received:2011-03-25 Online:2011-12-20 Published:2011-12-20
  • Supported by:

    Supported by the Province Key Science and Technology Program of Shanxi(No. 20090311031,2006031049),the International Cooperation Program of Shanxi(No. 2008081001-5,2007081001)and Key Science and Technology Program of Shanxi Academy of Agricultural Sciences(No. YGG0931)

摘要:

目的 测定北社鼠对杀鼠灵的敏感性,为检验该鼠的抗药性提供参数。方法 实验室做单个笼养无选择摄食试验:雌雄分开,随机分组,按5个不同食毒期供给浓度为0.025%的杀鼠灵毒饵;用Bliss计算机软件,计算不同食毒期与对应死亡率之间的关系。结果 北社鼠对杀鼠灵的敏感性,性别之间差异无统计学意义(Pb>0.05,PLFP50>0.05);故将雌雄数据合并计算,得毒力回归方程y=3.29+4.33x,LFP50、LFP95、LFP99 及其95%置信限分别为2.48(1.97~3.13)、5.96(3.92~9.06)和8.56(4.65~15.78)d。结论 按世界卫生组织推荐的以致死99%敏感靶标鼠的食毒期(LFP99)取整天数作为抗药性检验标准,山西省娄烦地区北社鼠对0.025%的杀鼠灵毒饵摄食期超过9 d存活即为抗性鼠。

关键词: 北社鼠, 抗凝血类灭鼠剂, 杀鼠灵, 敏感性

Abstract:

Objective To determine the susceptibility of Niviventer confucianus to warfarin. Methods Baits with 0. 025% warfarin were randomly given in single-sex groups of five feeding periods. The time to mortality was analyzed using the Bliss software. Results There was no significant difference in the susceptibility between sexes (Pb>0.05, PLFP50>0.05). The LFP50, LFP95 and LFP99 of warfarin for N. confucianus were 2.48 (1.97-3.13) days, 5.96 (3.92-9.06) days and 8.56 (4.65-15.78) days, respectively. Conclusion According to the WHO-recommended LFP99-based criteria for rodent warfarin resistance, N. confucianus surviving more than 9 days under exposure to 0.025% warfarin were classified into the resistant strains.

Key words: Niviventer confucianus, Anticoagulant rodenticide, Warfarin, Susceptibility

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